TY - JOUR
T1 - Rheumatoid arthritis mimicking metastatic squamous cell carcinoma
AU - Gomez-Rivera, Fernando
AU - El-Naggar, Adel K.
AU - Guha-Thakurta, Nandita
AU - Kupferman, Michael E.
PY - 2011
Y1 - 2011
N2 - We report a case of a cervical rheumatoid nodule in close relation to the hyoid bone mimicking a metastatic carcinoma. A 74-year-old female with a 15-year history of rheumatoid arthritis (RA) on treatment with methotrexate presented with tenderness of the right base of tongue. Imaging demonstrated a 1.4 cm cystic lesion at the hyoid bone. Biopsies were unsuccessful and the patient required surgical resection of the mass. A trans-cervical approach was used. Pathology revealed a necrotizing granuloma compatible with rheumatoid etiology. The clinician should be aware that, in a patient with a neck mass, in the presence of active RA, rheumatoid nodules should be part of the differential diagnosis.
AB - We report a case of a cervical rheumatoid nodule in close relation to the hyoid bone mimicking a metastatic carcinoma. A 74-year-old female with a 15-year history of rheumatoid arthritis (RA) on treatment with methotrexate presented with tenderness of the right base of tongue. Imaging demonstrated a 1.4 cm cystic lesion at the hyoid bone. Biopsies were unsuccessful and the patient required surgical resection of the mass. A trans-cervical approach was used. Pathology revealed a necrotizing granuloma compatible with rheumatoid etiology. The clinician should be aware that, in a patient with a neck mass, in the presence of active RA, rheumatoid nodules should be part of the differential diagnosis.
KW - Rheumatoid
KW - arthritis
KW - hyoid
KW - larynx
KW - nodule
UR - http://www.scopus.com/inward/record.url?scp=79955835296&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79955835296&partnerID=8YFLogxK
U2 - 10.1186/1758-3284-3-26
DO - 10.1186/1758-3284-3-26
M3 - Article
C2 - 21569598
AN - SCOPUS:79955835296
SN - 1758-3284
VL - 3
JO - Head and Neck Oncology
JF - Head and Neck Oncology
IS - 1
M1 - 26
ER -