TY - JOUR
T1 - Risk stratification for clinical severity of pulmonary embolism in patients with cancer
T2 - a narrative review and MASCC clinical guidance for daily care
AU - the Multinational Association of Supportive Care in Cancer (MASCC) Hemostasis Study Group
AU - Muñoz-Guglielmetti, Diego
AU - Cooksley, Tim
AU - Ahn, Shin
AU - Beato, Carmen
AU - Aramberri, Mario
AU - Escalante, Carmen
AU - Font, Carme
N1 - Publisher Copyright:
© 2022, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
PY - 2022/10
Y1 - 2022/10
N2 - Pulmonary embolism (PE) is a leading cause of morbidity and mortality in patients with cancer. The clinical presentation and outcomes of PE range from an acute life-threatening condition requiring intensive care to a mild symptomatic condition associated with favorable outcomes and potentially candidate for early hospital discharge. The wide clinical spectrum of PE has led to the development of risk stratification models aimed at the triage of patients in emergency care departments and optimizing the utilization of health care resources. Incidental or unsuspected PE (UPE), detected during routine staging computed tomography scans, make up a significant proportion of this cohort among the oncology population. The present narrative review is aimed at examining the currently available PE risk assessment models developed for the general population and for patients with cancer including UPE. We include general recommendations for the daily care of patients with cancer-related PE and hypothesize on the factors that would potentially favor hospitalization with early discharge or ambulatory management in this setting.
AB - Pulmonary embolism (PE) is a leading cause of morbidity and mortality in patients with cancer. The clinical presentation and outcomes of PE range from an acute life-threatening condition requiring intensive care to a mild symptomatic condition associated with favorable outcomes and potentially candidate for early hospital discharge. The wide clinical spectrum of PE has led to the development of risk stratification models aimed at the triage of patients in emergency care departments and optimizing the utilization of health care resources. Incidental or unsuspected PE (UPE), detected during routine staging computed tomography scans, make up a significant proportion of this cohort among the oncology population. The present narrative review is aimed at examining the currently available PE risk assessment models developed for the general population and for patients with cancer including UPE. We include general recommendations for the daily care of patients with cancer-related PE and hypothesize on the factors that would potentially favor hospitalization with early discharge or ambulatory management in this setting.
KW - Acute pulmonary embolism
KW - Cancer-associated venous thromboembolism
KW - Supportive care oncology
KW - Unsuspected pulmonary embolism
UR - http://www.scopus.com/inward/record.url?scp=85132169591&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85132169591&partnerID=8YFLogxK
U2 - 10.1007/s00520-022-07131-1
DO - 10.1007/s00520-022-07131-1
M3 - Article
C2 - 35579753
AN - SCOPUS:85132169591
SN - 0941-4355
VL - 30
SP - 8527
EP - 8538
JO - Supportive Care in Cancer
JF - Supportive Care in Cancer
IS - 10
ER -