RNA editing in cancer: Mechanistic, prognostic, and therapeutic implications

Leng Han; Han Liang

doi:10.1080/23723556.2015.1117702

RNA editing in cancer: Mechanistic, prognostic, and therapeutic implications

Leng Han, Han Liang

Bioinformatics & Computational Biology

Research output: Contribution to journal › Comment/debate › peer-review

7 Scopus citations

Abstract

We have recently provided a comprehensive analysis of A-to-I RNA editing events in various cancer types, revealing many clinically relevant RNA editing sites and demonstrating that RNA editing can selectively affect cancer drug sensitivity. Our results unveil mechanistic, prognostic, and therapeutic implications for RNA editing in cancer.

Original language	English (US)
Article number	e1117702
Journal	Molecular and Cellular Oncology
Volume	3
Issue number	2
DOIs	https://doi.org/10.1080/23723556.2015.1117702
State	Published - Mar 3 2016

Keywords

Driver events
RNA editing
drug sensitivity
pancancer analysis
prognostic marker

ASJC Scopus subject areas

Molecular Medicine
Cancer Research

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10.1080/23723556.2015.1117702

Cite this

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title = "RNA editing in cancer: Mechanistic, prognostic, and therapeutic implications",

abstract = "We have recently provided a comprehensive analysis of A-to-I RNA editing events in various cancer types, revealing many clinically relevant RNA editing sites and demonstrating that RNA editing can selectively affect cancer drug sensitivity. Our results unveil mechanistic, prognostic, and therapeutic implications for RNA editing in cancer.",

keywords = "Driver events, RNA editing, drug sensitivity, pancancer analysis, prognostic marker",

author = "Leng Han and Han Liang",

note = "Publisher Copyright: {\textcopyright} 2016, {\textcopyright} 2016 Taylor & Francis Group, LLC.",

year = "2016",

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AU - Han, Leng

AU - Liang, Han

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N2 - We have recently provided a comprehensive analysis of A-to-I RNA editing events in various cancer types, revealing many clinically relevant RNA editing sites and demonstrating that RNA editing can selectively affect cancer drug sensitivity. Our results unveil mechanistic, prognostic, and therapeutic implications for RNA editing in cancer.

AB - We have recently provided a comprehensive analysis of A-to-I RNA editing events in various cancer types, revealing many clinically relevant RNA editing sites and demonstrating that RNA editing can selectively affect cancer drug sensitivity. Our results unveil mechanistic, prognostic, and therapeutic implications for RNA editing in cancer.

KW - Driver events

KW - RNA editing

KW - drug sensitivity

KW - pancancer analysis

KW - prognostic marker

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RNA editing in cancer: Mechanistic, prognostic, and therapeutic implications

Abstract

Keywords

ASJC Scopus subject areas

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