RNAi in Cancer Therapy

Cristian Rodriguez-Aguayo; Arturo Chavez-Reyes; Gabriel Lopez-Berestein; Anil K. Sood

doi:10.1002/9781118610749.ch13

RNAi in Cancer Therapy

Cristian Rodriguez-Aguayo, Arturo Chavez-Reyes, Gabriel Lopez-Berestein, Anil K. Sood

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

This chapter discusses the therapeutic opportunities for ncRNA, approaches to overcoming anatomic and physiologic barriers to siRNA delivery, and recent advances in the design of delivery strategies for siRNA, with emphasis on in vivo delivery and intracellular trafficking of therapeutic RNA in cancer therapy.

Original language	English (US)
Title of host publication	Advanced Delivery and Therapeutic Applications of RNAi
Publisher	John Wiley and Sons
Pages	271-307
Number of pages	37
ISBN (Print)	9781119976868
DOIs	https://doi.org/10.1002/9781118610749.ch13
State	Published - Apr 26 2013

Keywords

Anatomic and physiologic barriers
Cancer
Intracellular delivery
Intravascular degradation
MiRNA
Noncoding RNAs
Off-target effects

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology
Pharmacology, Toxicology and Pharmaceutics(all)

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10.1002/9781118610749.ch13

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title = "RNAi in Cancer Therapy",

abstract = "This chapter discusses the therapeutic opportunities for ncRNA, approaches to overcoming anatomic and physiologic barriers to siRNA delivery, and recent advances in the design of delivery strategies for siRNA, with emphasis on in vivo delivery and intracellular trafficking of therapeutic RNA in cancer therapy.",

keywords = "Anatomic and physiologic barriers, Cancer, Intracellular delivery, Intravascular degradation, MiRNA, Noncoding RNAs, Off-target effects",

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AU - Chavez-Reyes, Arturo

AU - Lopez-Berestein, Gabriel

AU - Sood, Anil K.

PY - 2013/4/26

Y1 - 2013/4/26

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KW - Cancer

KW - Intracellular delivery

KW - Intravascular degradation

KW - MiRNA

KW - Noncoding RNAs

KW - Off-target effects

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BT - Advanced Delivery and Therapeutic Applications of RNAi

PB - John Wiley and Sons

ER -

RNAi in Cancer Therapy

Abstract

Keywords

ASJC Scopus subject areas

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