Role of intestinal microbiota in transplantation outcomes

Ying Taur; Robert R. Jenq; Carles Ubeda; Marcel Van Den Brink; Eric G. Pamer

doi:10.1016/j.beha.2015.10.013

Role of intestinal microbiota in transplantation outcomes

Ying Taur, Robert R. Jenq, Carles Ubeda, Marcel Van Den Brink, Eric G. Pamer

Research output: Contribution to journal › Review article › peer-review

48 Scopus citations

Abstract

While allogeneic hematopoietic stem cell transplantations have a curative potential, infections and graft-versus-host disease remain significant problems. The intestinal microbiota can influence responses to cancer chemotherapy and the role of the microbiota in affecting allogeneic hematopoietic stem cell transplantation outcomes is increasingly appreciated. The following paper discusses the most recent developments in this area.

Original language	English (US)
Pages (from-to)	155-161
Number of pages	7
Journal	Best Practice and Research: Clinical Haematology
Volume	28
Issue number	2-3
DOIs	https://doi.org/10.1016/j.beha.2015.10.013
State	Published - Jun 1 2015
Externally published	Yes

Keywords

Allo-HSCT
Bacteremia
Diversity
Intestinal microbiota
Metronidazole
Microbial dominance
Mortality
Survival

ASJC Scopus subject areas

Oncology
Clinical Biochemistry

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10.1016/j.beha.2015.10.013

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title = "Role of intestinal microbiota in transplantation outcomes",

abstract = "While allogeneic hematopoietic stem cell transplantations have a curative potential, infections and graft-versus-host disease remain significant problems. The intestinal microbiota can influence responses to cancer chemotherapy and the role of the microbiota in affecting allogeneic hematopoietic stem cell transplantation outcomes is increasingly appreciated. The following paper discusses the most recent developments in this area.",

keywords = "Allo-HSCT, Bacteremia, Diversity, Intestinal microbiota, Metronidazole, Microbial dominance, Mortality, Survival",

author = "Ying Taur and Jenq, {Robert R.} and Carles Ubeda and {Van Den Brink}, Marcel and Pamer, {Eric G.}",

year = "2015",

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T1 - Role of intestinal microbiota in transplantation outcomes

AU - Taur, Ying

AU - Jenq, Robert R.

AU - Ubeda, Carles

AU - Van Den Brink, Marcel

AU - Pamer, Eric G.

PY - 2015/6/1

Y1 - 2015/6/1

N2 - While allogeneic hematopoietic stem cell transplantations have a curative potential, infections and graft-versus-host disease remain significant problems. The intestinal microbiota can influence responses to cancer chemotherapy and the role of the microbiota in affecting allogeneic hematopoietic stem cell transplantation outcomes is increasingly appreciated. The following paper discusses the most recent developments in this area.

AB - While allogeneic hematopoietic stem cell transplantations have a curative potential, infections and graft-versus-host disease remain significant problems. The intestinal microbiota can influence responses to cancer chemotherapy and the role of the microbiota in affecting allogeneic hematopoietic stem cell transplantation outcomes is increasingly appreciated. The following paper discusses the most recent developments in this area.

KW - Allo-HSCT

KW - Bacteremia

KW - Diversity

KW - Intestinal microbiota

KW - Metronidazole

KW - Microbial dominance

KW - Mortality

KW - Survival

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U2 - 10.1016/j.beha.2015.10.013

DO - 10.1016/j.beha.2015.10.013

M3 - Review article

C2 - 26590773

AN - SCOPUS:84959861184

SN - 1521-6926

VL - 28

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EP - 161

JO - Best Practice and Research: Clinical Haematology

JF - Best Practice and Research: Clinical Haematology

IS - 2-3

ER -

Role of intestinal microbiota in transplantation outcomes

Abstract

Keywords

ASJC Scopus subject areas

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