SARS-CoV-2 re-infection versus prolonged shedding: A case series

Erin G. Nicholson; Vasanthi Avadhanula; Sonia Fragoso; Rachel Stroh; Xunyan Ye; Nanette Bond; Patricia Santarcangelo; John Stroh; Pedro A. Piedra

doi:10.1111/irv.12879

SARS-CoV-2 re-infection versus prolonged shedding: A case series

Erin G. Nicholson, Vasanthi Avadhanula, Sonia Fragoso, Rachel Stroh, Xunyan Ye, Nanette Bond, Patricia Santarcangelo, John Stroh, Pedro A. Piedra

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Since the start of the SARS-CoV-2 pandemic, it has been difficult to differentiate between SARS-CoV-2 re-infection and prolonged RNA shedding. In this report, we identified patients with positive RT-PCR results for SARS-CoV-2 ≥70 days apart. Clinical and laboratory data were collected and criteria were applied to discern whether the presentation was consistent with SARS-CoV-2 re-infection or prolonged viral RNA shedding. Eleven individuals met the initial testing criteria, of which, seven met at least one criteria for re-infection and four were consistent with prolonged RNA shedding. These data demonstrate the need for criteria to differentiate SARS-CoV-2 re-infection from prolonged RNA shedding.

Original language	English (US)
Pages (from-to)	691-696
Number of pages	6
Journal	Influenza and other Respiratory Viruses
Volume	15
Issue number	6
DOIs	https://doi.org/10.1111/irv.12879
State	Published - Nov 2021
Externally published	Yes

Keywords

re-infection
SARS-CoV-2
shedding

ASJC Scopus subject areas

Epidemiology
Pulmonary and Respiratory Medicine
Public Health, Environmental and Occupational Health
Infectious Diseases

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10.1111/irv.12879

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abstract = "Since the start of the SARS-CoV-2 pandemic, it has been difficult to differentiate between SARS-CoV-2 re-infection and prolonged RNA shedding. In this report, we identified patients with positive RT-PCR results for SARS-CoV-2 ≥70 days apart. Clinical and laboratory data were collected and criteria were applied to discern whether the presentation was consistent with SARS-CoV-2 re-infection or prolonged viral RNA shedding. Eleven individuals met the initial testing criteria, of which, seven met at least one criteria for re-infection and four were consistent with prolonged RNA shedding. These data demonstrate the need for criteria to differentiate SARS-CoV-2 re-infection from prolonged RNA shedding.",

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AU - Avadhanula, Vasanthi

AU - Fragoso, Sonia

AU - Stroh, Rachel

AU - Ye, Xunyan

AU - Bond, Nanette

AU - Santarcangelo, Patricia

AU - Stroh, John

AU - Piedra, Pedro A.

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SARS-CoV-2 re-infection versus prolonged shedding: A case series

Abstract

Keywords

ASJC Scopus subject areas

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