Scanning thermoacoustic tomography in biological tissue

Geng Ku, Lihong V. Wang

Research output: Contribution to journalArticlepeer-review

143 Scopus citations

Abstract

Microwave-induced thermoacoustic tomography was explored to image biological tissue. Short microwave pulses irradiated tissue to generate acoustic waves by thermoelastic expansion. The microwave-induced thermoacoustic waves were detected with a focused ultrasonic transducer. Each time-domain signal from the ultrasonic transducer represented a one- dimensional image along the acoustic axis of the ultrasonic transducer similar to an ultrasonic A-scan. Scanning the system perpendicularly to the acoustic axis of the ultrasonic transducer would generate multi-dimensional images. Two-dimensional tomographic images of biological tissue were obtained with 3-GHz microwaves. The axial and lateral resolutions were characterized. The time-domain piezo-electric signal from the ultrasonic transducer in response to the thermoacoustic signal was simulated theoretically, and the theoretical result agreed with the experimental result very well. (C) 2000 American Association of Physicists in Medicine.

Original languageEnglish (US)
Pages (from-to)1195-1202
Number of pages8
JournalMedical physics
Volume27
Issue number5
DOIs
StatePublished - May 2000

Keywords

  • Microwave
  • Photoacoustics
  • Thermoacoustics
  • Tomography
  • Ultrasonics

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging

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