Seeing SPIOs Directly In Vivo with Magnetic Particle Imaging

Bo Zheng; Elaine Yu; Ryan Orendorff; Kuan Lu; Justin J. Konkle; Zhi Wei Tay; Daniel Hensley; Xinyi Y. Zhou; Prashant Chandrasekharan; Emine U. Saritas; Patrick W. Goodwill; John D. Hazle; Steven M. Conolly

doi:10.1007/s11307-017-1081-y

Seeing SPIOs Directly In Vivo with Magnetic Particle Imaging

Bo Zheng, Elaine Yu, Ryan Orendorff, Kuan Lu, Justin J. Konkle, Zhi Wei Tay, Daniel Hensley, Xinyi Y. Zhou, Prashant Chandrasekharan, Emine U. Saritas, Patrick W. Goodwill, John D. Hazle, Steven M. Conolly

Imaging Physics

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

Magnetic particle imaging (MPI) is a new molecular imaging technique that directly images superparamagnetic tracers with high image contrast and sensitivity approaching nuclear medicine techniques—but without ionizing radiation. Since its inception, the MPI research field has quickly progressed in imaging theory, hardware, tracer design, and biomedical applications. Here, we describe the history and field of MPI, outline pressing challenges to MPI technology and clinical translation, highlight unique applications in MPI, and describe the role of the WMIS MPI Interest Group in collaboratively advancing MPI as a molecular imaging technique. We invite interested investigators to join the MPI Interest Group and contribute new insights and innovations to the MPI field.

Original language	English (US)
Pages (from-to)	385-390
Number of pages	6
Journal	Molecular Imaging and Biology
Volume	19
Issue number	3
DOIs	https://doi.org/10.1007/s11307-017-1081-y
State	Published - Jun 1 2017

Keywords

Interest group
Magnetic particle imaging
Superparamagnetic iron oxide

ASJC Scopus subject areas

Oncology
Radiology Nuclear Medicine and imaging
Cancer Research

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10.1007/s11307-017-1081-y

Cite this

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title = "Seeing SPIOs Directly In Vivo with Magnetic Particle Imaging",

abstract = "Magnetic particle imaging (MPI) is a new molecular imaging technique that directly images superparamagnetic tracers with high image contrast and sensitivity approaching nuclear medicine techniques—but without ionizing radiation. Since its inception, the MPI research field has quickly progressed in imaging theory, hardware, tracer design, and biomedical applications. Here, we describe the history and field of MPI, outline pressing challenges to MPI technology and clinical translation, highlight unique applications in MPI, and describe the role of the WMIS MPI Interest Group in collaboratively advancing MPI as a molecular imaging technique. We invite interested investigators to join the MPI Interest Group and contribute new insights and innovations to the MPI field.",

keywords = "Interest group, Magnetic particle imaging, Superparamagnetic iron oxide",

author = "Bo Zheng and Elaine Yu and Ryan Orendorff and Kuan Lu and Konkle, {Justin J.} and Tay, {Zhi Wei} and Daniel Hensley and Zhou, {Xinyi Y.} and Prashant Chandrasekharan and Saritas, {Emine U.} and Goodwill, {Patrick W.} and Hazle, {John D.} and Conolly, {Steven M.}",

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doi = "10.1007/s11307-017-1081-y",

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T1 - Seeing SPIOs Directly In Vivo with Magnetic Particle Imaging

AU - Zheng, Bo

AU - Yu, Elaine

AU - Orendorff, Ryan

AU - Lu, Kuan

AU - Konkle, Justin J.

AU - Tay, Zhi Wei

AU - Hensley, Daniel

AU - Zhou, Xinyi Y.

AU - Chandrasekharan, Prashant

AU - Saritas, Emine U.

AU - Goodwill, Patrick W.

AU - Hazle, John D.

AU - Conolly, Steven M.

PY - 2017/6/1

Y1 - 2017/6/1

N2 - Magnetic particle imaging (MPI) is a new molecular imaging technique that directly images superparamagnetic tracers with high image contrast and sensitivity approaching nuclear medicine techniques—but without ionizing radiation. Since its inception, the MPI research field has quickly progressed in imaging theory, hardware, tracer design, and biomedical applications. Here, we describe the history and field of MPI, outline pressing challenges to MPI technology and clinical translation, highlight unique applications in MPI, and describe the role of the WMIS MPI Interest Group in collaboratively advancing MPI as a molecular imaging technique. We invite interested investigators to join the MPI Interest Group and contribute new insights and innovations to the MPI field.

AB - Magnetic particle imaging (MPI) is a new molecular imaging technique that directly images superparamagnetic tracers with high image contrast and sensitivity approaching nuclear medicine techniques—but without ionizing radiation. Since its inception, the MPI research field has quickly progressed in imaging theory, hardware, tracer design, and biomedical applications. Here, we describe the history and field of MPI, outline pressing challenges to MPI technology and clinical translation, highlight unique applications in MPI, and describe the role of the WMIS MPI Interest Group in collaboratively advancing MPI as a molecular imaging technique. We invite interested investigators to join the MPI Interest Group and contribute new insights and innovations to the MPI field.

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KW - Superparamagnetic iron oxide

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Seeing SPIOs Directly In Vivo with Magnetic Particle Imaging

Abstract

Keywords

ASJC Scopus subject areas

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