Segmentation of contrast enhanced CT images for attenuation correction of PET/CT data

Feng Qiao, Yong Yue, Tinsu Pan, John W. Clark, Osama Mawlawi

Research output: Contribution to journalConference articlepeer-review

3 Scopus citations

Abstract

The use of contrast media in PET/CT imaging has been suggested to cause PET artifacts during the CT-based attenuation correction process. In this paper, we evaluate three algorithms that segment intravenous (IV) contrast-enhanced tissue from chest CT images to minimize possible artifacts. The algorithms that were evaluated are template matching, 3D region growing, and snake-based technique. These methods were tested using 5 patient studies. The segmentation result of each method was compared to its corresponding manually segmented images on a voxel-wise basis, and a squared difference between the two segmentation results was calculated. The averaged squared differences of all 5 patients for the template matching, region growing, and snake-based method were 19.0% ±7.1%, 65.2% ±51.5%, and 13.5% ±6.5% respectively. We concluded that the snake model is most suitable for efficiently segmenting the contrast-enhanced CT images among the three methods.

Original languageEnglish (US)
Pages (from-to)2686-2689
Number of pages4
JournalIEEE Nuclear Science Symposium Conference Record
Volume5
StatePublished - 2004
Event2004 Nuclear Science Symposium, Medical Imaging Conference, Symposium on Nuclear Power Systems and the 14th International Workshop on Room Temperature Semiconductor X- and Gamma- Ray Detectors - Rome, Italy
Duration: Oct 16 2004Oct 22 2004

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging

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