TY - JOUR
T1 - Seizures and Dermatitis After Exposure to Caprolactam
AU - Tuma, Samir N.
AU - Orson, Frank
AU - Fossella, Frank V.
AU - Waidhofer, William
PY - 1981/10
Y1 - 1981/10
N2 - A 22-year-old man was initially seen with dermatitis, fever, and seizures after three days of occupational exposure to caprolactam, a nylon fiber precursor. A comprehensive neurological investigation showed no organic CNS abnormalities. Although caprolactam has been shown to induce convulsive disorders in experimental animals, to our knowledge, there are no reports of caprolactam-induced seizures in man. The coincidence of typical skin lesions with otherwise unexplained grand mal seizures in this patient strongly suggests that caprolactam was the cause.
AB - A 22-year-old man was initially seen with dermatitis, fever, and seizures after three days of occupational exposure to caprolactam, a nylon fiber precursor. A comprehensive neurological investigation showed no organic CNS abnormalities. Although caprolactam has been shown to induce convulsive disorders in experimental animals, to our knowledge, there are no reports of caprolactam-induced seizures in man. The coincidence of typical skin lesions with otherwise unexplained grand mal seizures in this patient strongly suggests that caprolactam was the cause.
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U2 - 10.1001/archinte.1981.00340120152033
DO - 10.1001/archinte.1981.00340120152033
M3 - Article
C2 - 7283571
AN - SCOPUS:0019464002
SN - 0003-9926
VL - 141
SP - 1544
EP - 1545
JO - Archives of Internal Medicine
JF - Archives of Internal Medicine
IS - 11
ER -