TY - JOUR
T1 - Sentinel node biopsy as a tool for accurate staging of eyelid and conjunctival malignancies
AU - Esmaeli, Bita
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2002/10
Y1 - 2002/10
N2 - Sentinel lymph node (SLN) biopsy has emerged as a technique for accurate staging of solid tumors. This technique permits the detection of microscopic metastases in clinically negative regional lymph nodes and may be indicated for malignancies that have a propensity for regional nodal metastasis. With the exception of basal cell carcinoma, almost all malignancies of the eyelid and conjunctiva metastasize to regional lymph nodes as the site of first metastasis. The histologic status of the SLNs has been shown to be the most significant prognostic factor with respect to recurrence and survival in patients with cutaneous melanoma. The indications for and the feasibility of SLN biopsy for eyelid and conjunctival tumors and our experience with this technique are reviewed.
AB - Sentinel lymph node (SLN) biopsy has emerged as a technique for accurate staging of solid tumors. This technique permits the detection of microscopic metastases in clinically negative regional lymph nodes and may be indicated for malignancies that have a propensity for regional nodal metastasis. With the exception of basal cell carcinoma, almost all malignancies of the eyelid and conjunctiva metastasize to regional lymph nodes as the site of first metastasis. The histologic status of the SLNs has been shown to be the most significant prognostic factor with respect to recurrence and survival in patients with cutaneous melanoma. The indications for and the feasibility of SLN biopsy for eyelid and conjunctival tumors and our experience with this technique are reviewed.
UR - http://www.scopus.com/inward/record.url?scp=0036790173&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036790173&partnerID=8YFLogxK
U2 - 10.1097/00055735-200210000-00005
DO - 10.1097/00055735-200210000-00005
M3 - Review article
C2 - 12218463
AN - SCOPUS:0036790173
SN - 1040-8738
VL - 13
SP - 317
EP - 323
JO - Current opinion in ophthalmology
JF - Current opinion in ophthalmology
IS - 5
ER -