Serum and cerebrospinal fluid immunoglobulins M, A, and G in Japanese encephalitis

X. Y. Han, Q. W. Ren, Z. Y. Xu, T. F. Tsai

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

A comparison was made of virus-specific immunoglobulin M (IgM), IgA, and IgG detected by capture or indirect enzyme immunoassay in serum and cerebrospinal fluid of patients with Japanese encephalitis. The IgM capture enzyme immunoassay was more sensitive than assays for other isotypes of viral antibody; IgM was detected in 75% of specimens collected ≤ 4 days after the onset of illness. Specific IgA was detected in both serum and cerebrospinal fluid; however, IgA levels were significantly lower than IgM levels.

Original languageEnglish (US)
Pages (from-to)976-978
Number of pages3
JournalJournal of Clinical Microbiology
Volume26
Issue number5
DOIs
StatePublished - 1988

ASJC Scopus subject areas

  • Microbiology (medical)

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