Sex cord-stromal tumors

Jubilee Brown, David M. Gershenson

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

Sex cord-stromal tumors are rare neoplasms which most commonly occur in the ovary. Granulosa cell tumors are the most common histologic subtype. Presenting symptoms and signs may be specific to this group of tumors, and treatment is determined by many factors, including age and histologic subtype. Appropriate therapy usually includes surgery, and chemotherapy often plays a role. Much progress has recently been made in the field of sex cord-stromal tumors, with regard to fertility-sparing surgery, surgical staging, less toxic chemotherapy, useful biologic agents, and the genetic etiology of granulosa cell tumors. These advances and the management of patients with sex cord-stromal tumors are comprehensively reviewed in this chapter.

Original languageEnglish (US)
Title of host publicationRare and Uncommon Gynecological Cancers
Subtitle of host publicationA Clinical Guide
PublisherSpringer Berlin Heidelberg
Pages113-130
Number of pages18
ISBN (Print)9783642134913
DOIs
StatePublished - 2011

ASJC Scopus subject areas

  • General Medicine

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