Abstract
The new World Health Organization classification of brain tumors depends on combining the histologic light microscopy features of central nervous system (CNS) tumors with canonical genetic alterations. This integrated diagnosis is redrawing the pedigree chart of brain tumors with rearrangement of tumor groups on the basis of geno-phenotypical behaviors into meaningful groups. Multiple radiogenomic studies provide a bridge between imaging features and tumor microenvironment. An overlap that can be integrated within the genophenotypical classification of CNS tumors for a better understanding of different clinically relevant entities.
Original language | English (US) |
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Pages (from-to) | 741-749 |
Number of pages | 9 |
Journal | Magnetic resonance imaging clinics of North America |
Volume | 24 |
Issue number | 4 |
DOIs | |
State | Published - Nov 1 2016 |
Keywords
- Central nervous system
- Radiogenomic
- Radiomics
- Tumors
- WHO Classification
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging