Signaling and cell death in lymphocytes

R. A. Flavell; C. Dong; R. J. Davis

doi:10.1007/BF02684006

Signaling and cell death in lymphocytes

R. A. Flavell, C. Dong, R. J. Davis

Immunology

Research output: Contribution to journal › Review article › peer-review

17 Scopus citations

Abstract

After activation, CD4 helper T(Th) cells differentiate into Th1 or Th2 effector cells. These two subsets produce distinct profiles of cytokines and regulate different immune responses. Here we discuss transcription factors and signaling pathways that are selectively expressed or activated in Th1 and Th2 cells to regulate cytokine gene expression, cell proliferation and apoptosis.

Original language	English (US)
Pages (from-to)	80-82
Number of pages	3
Journal	Inflammation Research
Volume	51
Issue number	2
DOIs	https://doi.org/10.1007/BF02684006
State	Published - 2002

Keywords

MAP kinases
T lymphocytes
Th1/Th2
Transcription factor

ASJC Scopus subject areas

Immunology
Pharmacology

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10.1007/BF02684006

Cite this

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title = "Signaling and cell death in lymphocytes",

abstract = "After activation, CD4 helper T(Th) cells differentiate into Th1 or Th2 effector cells. These two subsets produce distinct profiles of cytokines and regulate different immune responses. Here we discuss transcription factors and signaling pathways that are selectively expressed or activated in Th1 and Th2 cells to regulate cytokine gene expression, cell proliferation and apoptosis.",

keywords = "MAP kinases, T lymphocytes, Th1/Th2, Transcription factor",

author = "Flavell, {R. A.} and C. Dong and Davis, {R. J.}",

year = "2002",

doi = "10.1007/BF02684006",

language = "English (US)",

volume = "51",

pages = "80--82",

journal = "Inflammation Research",

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TY - JOUR

T1 - Signaling and cell death in lymphocytes

AU - Flavell, R. A.

AU - Dong, C.

AU - Davis, R. J.

PY - 2002

Y1 - 2002

N2 - After activation, CD4 helper T(Th) cells differentiate into Th1 or Th2 effector cells. These two subsets produce distinct profiles of cytokines and regulate different immune responses. Here we discuss transcription factors and signaling pathways that are selectively expressed or activated in Th1 and Th2 cells to regulate cytokine gene expression, cell proliferation and apoptosis.

AB - After activation, CD4 helper T(Th) cells differentiate into Th1 or Th2 effector cells. These two subsets produce distinct profiles of cytokines and regulate different immune responses. Here we discuss transcription factors and signaling pathways that are selectively expressed or activated in Th1 and Th2 cells to regulate cytokine gene expression, cell proliferation and apoptosis.

KW - MAP kinases

KW - T lymphocytes

KW - Th1/Th2

KW - Transcription factor

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U2 - 10.1007/BF02684006

DO - 10.1007/BF02684006

M3 - Review article

C2 - 11926317

AN - SCOPUS:0036192062

SN - 1023-3830

VL - 51

SP - 80

EP - 82

JO - Inflammation Research

JF - Inflammation Research

IS - 2

ER -

Signaling and cell death in lymphocytes

Abstract

Keywords

ASJC Scopus subject areas

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