TY - JOUR
T1 - Simultaneous Scalp, Skull, Kidney, and Pancreas Transplant from a Single Donor
T2 - Insights from a 5-Year Follow-Up
AU - Jozaghi, Yelda
AU - Chang, Edward I.
AU - Clemens, Mark W.
AU - Hanasono, Matthew M.
AU - Klebuc, Michael
AU - Yu, Peirong
AU - Gaber, A. Osama
AU - Selber, Jesse C.
N1 - Publisher Copyright:
© 2023 Lippincott Williams and Wilkins. All rights reserved.
PY - 2023/6/1
Y1 - 2023/6/1
N2 - Summary: This report provides a 5-year follow-up on the first reported simultaneous scalp, calvarium, kidney, and pancreas transplant. The previously published case report represented both the first composite calvarial-scalp transplant and combination of a vascularized composite allotransplantation with double organ transplantation. Over the ensuing 5 years, the patient underwent a single episode of acute scalp rejection successfully managed with intravenous Solu-Medrol, one resection of a basal cell carcinoma on the native scalp, hardware removal, and bony contouring. In addition, the patient developed seizures secondary to delayed, postirradiation cerebral necrosis requiring craniotomy and resection. His seizures were ultimately controlled. Currently, more than 5 years after his multiorgan transplant, the patient continues to have excellent allograft function and a very satisfactory aesthetic outcome, demonstrating that in certain cases, combined vascularized composite allotransplantation with solid organ transplantation can be performed safely without compromising the solid organ transplantation.
AB - Summary: This report provides a 5-year follow-up on the first reported simultaneous scalp, calvarium, kidney, and pancreas transplant. The previously published case report represented both the first composite calvarial-scalp transplant and combination of a vascularized composite allotransplantation with double organ transplantation. Over the ensuing 5 years, the patient underwent a single episode of acute scalp rejection successfully managed with intravenous Solu-Medrol, one resection of a basal cell carcinoma on the native scalp, hardware removal, and bony contouring. In addition, the patient developed seizures secondary to delayed, postirradiation cerebral necrosis requiring craniotomy and resection. His seizures were ultimately controlled. Currently, more than 5 years after his multiorgan transplant, the patient continues to have excellent allograft function and a very satisfactory aesthetic outcome, demonstrating that in certain cases, combined vascularized composite allotransplantation with solid organ transplantation can be performed safely without compromising the solid organ transplantation.
UR - http://www.scopus.com/inward/record.url?scp=85160209916&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85160209916&partnerID=8YFLogxK
U2 - 10.1097/PRS.0000000000010103
DO - 10.1097/PRS.0000000000010103
M3 - Article
C2 - 36729732
AN - SCOPUS:85160209916
SN - 0032-1052
VL - 151
SP - 1318
EP - 1321
JO - Plastic and reconstructive surgery
JF - Plastic and reconstructive surgery
IS - 6
ER -