SITC 2018 workshop report: Immuno-Oncology Biomarkers: State of the Art

Lisa H. Butterfield; Mary L. Disis; Bernard A. Fox; David R. Kaufman; Samir N. Khleif; Ena Wang; Helen Chen; William D. Merritt; Sacha Gnjatic; Kara Davis; Ignacio Wistuba; James Lindsay; Stacey Adam; Fred Ramsdell; Kellie N. Smith; Davide Bedognetti; Chen Zhao; Evan Newell; Michael Angelo; David Furman; Marta Luksza; Pier Federico Gherardini; Priti Hegde; Martin Cheever; Steven Fling; Shawn Sweeney; Hongyue Dai; Catharine Young; John M. Kirkwood; Yana Najjar; Randy Sweis; Theresa Lavallee; Holden T. Maecker; Zoe Quandt

doi:10.1186/s40425-018-0453-4

SITC 2018 workshop report: Immuno-Oncology Biomarkers: State of the Art

Lisa H. Butterfield, Mary L. Disis, Bernard A. Fox, David R. Kaufman, Samir N. Khleif, Ena Wang, Helen Chen, William D. Merritt, Sacha Gnjatic, Kara Davis, Ignacio Wistuba, James Lindsay, Stacey Adam, Fred Ramsdell, Kellie N. Smith, Davide Bedognetti, Chen Zhao, Evan Newell, Michael Angelo, David FurmanMarta Luksza, Pier Federico Gherardini, Priti Hegde, Martin Cheever, Steven Fling, Shawn Sweeney, Hongyue Dai, Catharine Young, John M. Kirkwood, Yana Najjar, Randy Sweis, Theresa Lavallee, Holden T. Maecker, Zoe Quandt

Translational Molecular Pathology

Research output: Contribution to journal › Review article › peer-review

16 Scopus citations

Abstract

Identification of biomarkers in cancer immunotherapy that predict therapeutic response and/or limit adverse events are a critical need in the field. To address recent progress and hurdles around cancer biomarker development and utilization, the Society for Immunotherapy of Cancer (SITC) convened a workshop, "Immuno-Oncology Biomarkers: State of the Art," on May 16-17, 2018. Topics discussed included challenges in handling biospecimens, identification and validation of new biomarkers, data sharing, and collaborating across disciplines to advance biomarker development. Panel discussions followed session presentations to help foster participant conversation and discuss future projects and collaborations. The results of the Workshop include the development of new initiatives for the SITC Biomarkers Committee.

Original language	English (US)
Article number	138
Journal	Journal for immunotherapy of cancer
Volume	6
Issue number	1
DOIs	https://doi.org/10.1186/s40425-018-0453-4
State	Published - Dec 4 2018

Keywords

Biomarkers
Cancer immunotherapy
Checkpoint inhibitor
PD-1/PD-L1

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Molecular Medicine
Oncology
Pharmacology
Cancer Research

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Butterfield, L. H., Disis, M. L., Fox, B. A., Kaufman, D. R., Khleif, S. N., Wang, E., Chen, H., Merritt, W. D., Gnjatic, S., Davis, K., Wistuba, I., Lindsay, J., Adam, S., Ramsdell, F., Smith, K. N., Bedognetti, D., Zhao, C., Newell, E., Angelo, M., ... Quandt, Z. (2018). SITC 2018 workshop report: Immuno-Oncology Biomarkers: State of the Art. Journal for immunotherapy of cancer, 6(1), Article 138. https://doi.org/10.1186/s40425-018-0453-4

Butterfield, LH, Disis, ML, Fox, BA, Kaufman, DR, Khleif, SN, Wang, E, Chen, H, Merritt, WD, Gnjatic, S, Davis, K, Wistuba, I, Lindsay, J, Adam, S, Ramsdell, F, Smith, KN, Bedognetti, D, Zhao, C, Newell, E, Angelo, M, Furman, D, Luksza, M, Gherardini, PF, Hegde, P, Cheever, M, Fling, S, Sweeney, S, Dai, H, Young, C, Kirkwood, JM, Najjar, Y, Sweis, R, Lavallee, T, Maecker, HT & Quandt, Z 2018, 'SITC 2018 workshop report: Immuno-Oncology Biomarkers: State of the Art', Journal for immunotherapy of cancer, vol. 6, no. 1, 138. https://doi.org/10.1186/s40425-018-0453-4

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abstract = "Identification of biomarkers in cancer immunotherapy that predict therapeutic response and/or limit adverse events are a critical need in the field. To address recent progress and hurdles around cancer biomarker development and utilization, the Society for Immunotherapy of Cancer (SITC) convened a workshop, {"}Immuno-Oncology Biomarkers: State of the Art,{"} on May 16-17, 2018. Topics discussed included challenges in handling biospecimens, identification and validation of new biomarkers, data sharing, and collaborating across disciplines to advance biomarker development. Panel discussions followed session presentations to help foster participant conversation and discuss future projects and collaborations. The results of the Workshop include the development of new initiatives for the SITC Biomarkers Committee.",

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doi = "10.1186/s40425-018-0453-4",

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AU - Butterfield, Lisa H.

AU - Disis, Mary L.

AU - Fox, Bernard A.

AU - Kaufman, David R.

AU - Khleif, Samir N.

AU - Wang, Ena

AU - Chen, Helen

AU - Merritt, William D.

AU - Gnjatic, Sacha

AU - Davis, Kara

AU - Wistuba, Ignacio

AU - Lindsay, James

AU - Adam, Stacey

AU - Ramsdell, Fred

AU - Smith, Kellie N.

AU - Bedognetti, Davide

AU - Zhao, Chen

AU - Newell, Evan

AU - Angelo, Michael

AU - Furman, David

AU - Luksza, Marta

AU - Gherardini, Pier Federico

AU - Hegde, Priti

AU - Cheever, Martin

AU - Fling, Steven

AU - Sweeney, Shawn

AU - Dai, Hongyue

AU - Young, Catharine

AU - Kirkwood, John M.

AU - Najjar, Yana

AU - Sweis, Randy

AU - Lavallee, Theresa

AU - Maecker, Holden T.

AU - Quandt, Zoe

PY - 2018/12/4

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N2 - Identification of biomarkers in cancer immunotherapy that predict therapeutic response and/or limit adverse events are a critical need in the field. To address recent progress and hurdles around cancer biomarker development and utilization, the Society for Immunotherapy of Cancer (SITC) convened a workshop, "Immuno-Oncology Biomarkers: State of the Art," on May 16-17, 2018. Topics discussed included challenges in handling biospecimens, identification and validation of new biomarkers, data sharing, and collaborating across disciplines to advance biomarker development. Panel discussions followed session presentations to help foster participant conversation and discuss future projects and collaborations. The results of the Workshop include the development of new initiatives for the SITC Biomarkers Committee.

AB - Identification of biomarkers in cancer immunotherapy that predict therapeutic response and/or limit adverse events are a critical need in the field. To address recent progress and hurdles around cancer biomarker development and utilization, the Society for Immunotherapy of Cancer (SITC) convened a workshop, "Immuno-Oncology Biomarkers: State of the Art," on May 16-17, 2018. Topics discussed included challenges in handling biospecimens, identification and validation of new biomarkers, data sharing, and collaborating across disciplines to advance biomarker development. Panel discussions followed session presentations to help foster participant conversation and discuss future projects and collaborations. The results of the Workshop include the development of new initiatives for the SITC Biomarkers Committee.

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KW - Cancer immunotherapy

KW - Checkpoint inhibitor

KW - PD-1/PD-L1

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SITC 2018 workshop report: Immuno-Oncology Biomarkers: State of the Art

Abstract

Keywords

ASJC Scopus subject areas

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