TY - JOUR
T1 - Spectrum of medication-induced complications in the abdomen
T2 - Role of cross-sectional imaging
AU - Shanbhogue, Alampady Krishna Prasad
AU - Virmani, Vivek
AU - Vikram, Raghu
AU - Prasad, Srinivasa R.
AU - Shanbhogue, Divya K.P.
AU - Nagar, Arpit
AU - Fasih, Najla
N1 - Copyright:
Copyright 2011 Elsevier B.V., All rights reserved.
PY - 2011/8
Y1 - 2011/8
N2 - OBJECTIVE. This article provides a comprehensive review of the role of MDCT and MRI in the diagnosis of drug-induced complications in the abdomen and pelvis in adults. A systematic organ-based review of these complications is presented, including but not limited to hepatic changes after chemotherapy, renal complications such as tumor lysis syndrome and lithium nephropathy, gastrointestinal manifestations, various opportunistic infections and secondary neoplasms, mycotic aortic aneurysm from intravesical bacille Calmette-Guérin, complications of anticoagulant therapy, and oral contraceptives. CONCLUSION. Advancements in imaging have led to recognition of radiologic features of previously unsuspected diseases. Occasionally, imaging may also identify effects of treatments instituted for these diseases. Consequently, imaging plays a critical role in the accurate diagnosis of a broad spectrum of drug-induced complications in the abdomen, both in emergent and nonemergent settings. Knowledge of the natural history, clinical manifestations, and salient imaging features of these entities is crucial to facilitate accurate clinical diagnosis in a timely fashion.
AB - OBJECTIVE. This article provides a comprehensive review of the role of MDCT and MRI in the diagnosis of drug-induced complications in the abdomen and pelvis in adults. A systematic organ-based review of these complications is presented, including but not limited to hepatic changes after chemotherapy, renal complications such as tumor lysis syndrome and lithium nephropathy, gastrointestinal manifestations, various opportunistic infections and secondary neoplasms, mycotic aortic aneurysm from intravesical bacille Calmette-Guérin, complications of anticoagulant therapy, and oral contraceptives. CONCLUSION. Advancements in imaging have led to recognition of radiologic features of previously unsuspected diseases. Occasionally, imaging may also identify effects of treatments instituted for these diseases. Consequently, imaging plays a critical role in the accurate diagnosis of a broad spectrum of drug-induced complications in the abdomen, both in emergent and nonemergent settings. Knowledge of the natural history, clinical manifestations, and salient imaging features of these entities is crucial to facilitate accurate clinical diagnosis in a timely fashion.
KW - Abdomen
KW - Complication
KW - Cross-sectional imaging
KW - Medication
UR - http://www.scopus.com/inward/record.url?scp=79960718882&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79960718882&partnerID=8YFLogxK
U2 - 10.2214/AJR.10.5415
DO - 10.2214/AJR.10.5415
M3 - Review article
C2 - 21785055
AN - SCOPUS:79960718882
SN - 0361-803X
VL - 197
SP - W286-W294
JO - American Journal of Roentgenology
JF - American Journal of Roentgenology
IS - 2
ER -