Spontaneous regression of interdigitating dendritic sarcoma in a patient with concurrent small lymphocytic lymphoma

Tamer Khashab; Lalit Sehgal; L. Jeffrey Medeiros; Felipe Samaniego

doi:10.1136/bcr-2014-209014

Spontaneous regression of interdigitating dendritic sarcoma in a patient with concurrent small lymphocytic lymphoma

Tamer Khashab, Lalit Sehgal, L. Jeffrey Medeiros, Felipe Samaniego

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Interdigitating dendritic cell sarcoma (IDCS) is a rare tumour; only seven cases of IDCS associated with chronic lymphocytic leucaemia/small lymphocytic lymphoma (CLL/SLL) have been reported. We present the case of a 60-year-old man who presented with fevers, night sweats and significant unintentional weight loss. Investigations led to a diagnosis of synchronous SLL and IDCS. Subsequent fluorodeoxyglucose (FDG) positron emission tomography CT (PET-CT) imaging revealed an unusual clinical course with spontaneously resolving highly metabolic lesions. After 42 months of follow-up, the patient remains free of clinical symptoms and evidence of IDCS.

Original language	English (US)
Article number	209014
Journal	BMJ Case Reports
Volume	2015
DOIs	https://doi.org/10.1136/bcr-2014-209014
State	Published - Jun 12 2015

ASJC Scopus subject areas

General Medicine

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title = "Spontaneous regression of interdigitating dendritic sarcoma in a patient with concurrent small lymphocytic lymphoma",

abstract = "Interdigitating dendritic cell sarcoma (IDCS) is a rare tumour; only seven cases of IDCS associated with chronic lymphocytic leucaemia/small lymphocytic lymphoma (CLL/SLL) have been reported. We present the case of a 60-year-old man who presented with fevers, night sweats and significant unintentional weight loss. Investigations led to a diagnosis of synchronous SLL and IDCS. Subsequent fluorodeoxyglucose (FDG) positron emission tomography CT (PET-CT) imaging revealed an unusual clinical course with spontaneously resolving highly metabolic lesions. After 42 months of follow-up, the patient remains free of clinical symptoms and evidence of IDCS.",

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AU - Khashab, Tamer

AU - Sehgal, Lalit

AU - Medeiros, L. Jeffrey

AU - Samaniego, Felipe

PY - 2015/6/12

Y1 - 2015/6/12

N2 - Interdigitating dendritic cell sarcoma (IDCS) is a rare tumour; only seven cases of IDCS associated with chronic lymphocytic leucaemia/small lymphocytic lymphoma (CLL/SLL) have been reported. We present the case of a 60-year-old man who presented with fevers, night sweats and significant unintentional weight loss. Investigations led to a diagnosis of synchronous SLL and IDCS. Subsequent fluorodeoxyglucose (FDG) positron emission tomography CT (PET-CT) imaging revealed an unusual clinical course with spontaneously resolving highly metabolic lesions. After 42 months of follow-up, the patient remains free of clinical symptoms and evidence of IDCS.

AB - Interdigitating dendritic cell sarcoma (IDCS) is a rare tumour; only seven cases of IDCS associated with chronic lymphocytic leucaemia/small lymphocytic lymphoma (CLL/SLL) have been reported. We present the case of a 60-year-old man who presented with fevers, night sweats and significant unintentional weight loss. Investigations led to a diagnosis of synchronous SLL and IDCS. Subsequent fluorodeoxyglucose (FDG) positron emission tomography CT (PET-CT) imaging revealed an unusual clinical course with spontaneously resolving highly metabolic lesions. After 42 months of follow-up, the patient remains free of clinical symptoms and evidence of IDCS.

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Spontaneous regression of interdigitating dendritic sarcoma in a patient with concurrent small lymphocytic lymphoma

Abstract

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