Abstract
Squamous cell carcinoma of the head and neck has been strongly linked to chronic tobacco and alcohol abuse. However, we are increasingly recognizing subgroups of patients without traditional risk factors. Recent clinical and molecular investigations suggest that there are distinctive clinical entities, particularly affecting young patients with cancers of the oral tongue and oropharynx. We review data from clinical observations and current biologic inquiries and consider therapeutic implications for these important patient subgroups.
Original language | English (US) |
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Pages (from-to) | 176-182 |
Number of pages | 7 |
Journal | Current opinion in oncology |
Volume | 13 |
Issue number | 3 |
DOIs | |
State | Published - 2001 |
ASJC Scopus subject areas
- Oncology
- Cancer Research