TY - JOUR
T1 - Staging and prognosis of cutaneous melanoma
AU - Dickson, Paxton V.
AU - Gershenwald, Jeffrey E.
N1 - Funding Information:
This work was supported in part by The University of Texas MD Anderson Cancer Center Melanoma SPORE ( P50 CA93459 ) and the Grossman Family Foundation .
PY - 2011/1
Y1 - 2011/1
N2 - Staging of cutaneous melanoma continues to evolve through identification and rigorous analysis of potential prognostic factors. In 1998, the American Joint Committee on Cancer (AJCC) Melanoma Staging Committee developed the AJCC melanoma staging database, an international integrated compilation of prospectively accumulated melanoma outcome data from several centers and clinical trial cooperative groups. Analysis of this database resulted in major revisions to the TNM staging system reflected in the sixth edition of the AJCC Cancer Staging Manual published in 2002. More recently, the committee's analysis of an updated melanoma staging database, including prospective data on more than 50,000 patients, led to staging revisions adopted in the seventh edition of the AJCC Cancer Staging Manual published in 2009. This article highlights these revisions, reviews relevant prognostic factors and their impact on staging, and discusses emerging tools that will likely affect future staging systems and clinical practice.
AB - Staging of cutaneous melanoma continues to evolve through identification and rigorous analysis of potential prognostic factors. In 1998, the American Joint Committee on Cancer (AJCC) Melanoma Staging Committee developed the AJCC melanoma staging database, an international integrated compilation of prospectively accumulated melanoma outcome data from several centers and clinical trial cooperative groups. Analysis of this database resulted in major revisions to the TNM staging system reflected in the sixth edition of the AJCC Cancer Staging Manual published in 2002. More recently, the committee's analysis of an updated melanoma staging database, including prospective data on more than 50,000 patients, led to staging revisions adopted in the seventh edition of the AJCC Cancer Staging Manual published in 2009. This article highlights these revisions, reviews relevant prognostic factors and their impact on staging, and discusses emerging tools that will likely affect future staging systems and clinical practice.
KW - Melanoma
KW - Prognosis
KW - Staging
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U2 - 10.1016/j.soc.2010.09.007
DO - 10.1016/j.soc.2010.09.007
M3 - Review article
C2 - 21111956
AN - SCOPUS:78649460689
SN - 1055-3207
VL - 20
SP - 1
EP - 17
JO - Surgical oncology clinics of North America
JF - Surgical oncology clinics of North America
IS - 1
ER -