Stereotactic body radiotherapy for spinal metastases: Current status, with a focus on its application in the postoperative patient. A review

Arjun Sahgal, Mark Bilsky, Eric L. Chang, Lijun Ma, Yoshiya Yamada, Laurence D. Rhines, Daniel Létournea, Matthew Foote, Eugene Yu, David A. Larson, Michael G. Fehlings

Research output: Contribution to journalReview articlepeer-review

169 Scopus citations

Abstract

Stereotactic body radiotherapy (SBRT) for spinal metastases is an emerging therapeutic option aimed at delivering high biologically effective doses to metastases while sparing the adjacent normal tissues. This technique has emerged following advances in radiation delivery that include sophisticated radiation treatment planning software, body immobilization devices, and capabilities of detecting and correcting patient positional deviations with imageguided radiotherapy. There are limited clinical data specifically supporting the role of SBRT as a superior alternative to conventional radiation in the postoperative patient. The focus of this review was to examine the evidence pertaining to spine SBRT in the treatment of spinal metastases and to provide a comprehensive analysis of published patterns of failure, with emphasis on the postoperative patient.

Original languageEnglish (US)
Pages (from-to)151-166
Number of pages16
JournalJournal of Neurosurgery: Spine
Volume14
Issue number2
DOIs
StatePublished - Feb 2011

Keywords

  • Malignant epidural spinal cord compression
  • Postoperative radiation
  • Spinal metastasis
  • Spine radiosurgery
  • Spine stereotactic body radiotherapy

ASJC Scopus subject areas

  • Surgery
  • Neurology
  • Clinical Neurology

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