Studies in heterochromatin DNA: Characterization of transcripts synthesized in situ from C-banded preparations

M. Tien Kuo; T. C. Hsu

doi:10.1007/BF00286412

Studies in heterochromatin DNA: Characterization of transcripts synthesized in situ from C-banded preparations

M. Tien Kuo, T. C. Hsu

Translational Molecular Pathology

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Abstract

The transcript of in situ RNA synthesis using Peromyscus eremicus cells, which had been treated with HCl followed by NaOH, proved to be rich in heterochromatin specifying sequences. Such transcript, referred to as heterochromatin RNA, can be characterized biochemically to probe the organization of heterochromatin DNA. It was found that the heterochromatin RNA of P. eremicus contained non-repetitive sequences covalently linked to repetitive sequences.

Original language	English (US)
Pages (from-to)	325-334
Number of pages	10
Journal	Chromosoma
Volume	65
Issue number	4
DOIs	https://doi.org/10.1007/BF00286412
State	Published - Dec 1978

ASJC Scopus subject areas

Genetics
Genetics(clinical)

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title = "Studies in heterochromatin DNA: Characterization of transcripts synthesized in situ from C-banded preparations",

abstract = "The transcript of in situ RNA synthesis using Peromyscus eremicus cells, which had been treated with HCl followed by NaOH, proved to be rich in heterochromatin specifying sequences. Such transcript, referred to as heterochromatin RNA, can be characterized biochemically to probe the organization of heterochromatin DNA. It was found that the heterochromatin RNA of P. eremicus contained non-repetitive sequences covalently linked to repetitive sequences.",

author = "Kuo, {M. Tien} and Hsu, {T. C.}",

year = "1978",

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N2 - The transcript of in situ RNA synthesis using Peromyscus eremicus cells, which had been treated with HCl followed by NaOH, proved to be rich in heterochromatin specifying sequences. Such transcript, referred to as heterochromatin RNA, can be characterized biochemically to probe the organization of heterochromatin DNA. It was found that the heterochromatin RNA of P. eremicus contained non-repetitive sequences covalently linked to repetitive sequences.

AB - The transcript of in situ RNA synthesis using Peromyscus eremicus cells, which had been treated with HCl followed by NaOH, proved to be rich in heterochromatin specifying sequences. Such transcript, referred to as heterochromatin RNA, can be characterized biochemically to probe the organization of heterochromatin DNA. It was found that the heterochromatin RNA of P. eremicus contained non-repetitive sequences covalently linked to repetitive sequences.

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Studies in heterochromatin DNA: Characterization of transcripts synthesized in situ from C-banded preparations

Abstract

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