Successful treatment of metachronous contralateral intratubular germ cell neoplasia with partial orchiectomy and low-dose radiation in a patient previously treated for testicular carcinoma

Netta Schneller, Amanda Grimes, Jodi Muscal, Norma Quintanilla, Angela Mittal, Arnold Paulino, Jennifer Foster

Research output: Contribution to journalArticlepeer-review

Abstract

Intratubular germ cell neoplasia (ITGCN) of the testis is a precursor to testicular germ cell tumor (TGCT), which can lead to the development of invasive cancer. In patients with a history of previously treated unilateral TGCT, treatment for ITGCN of the contralateral testis needs to be balanced with the risks of subsequent infertility. Here, we present a 17- year- old patient with ITGCN diagnosed after treatment of contralateral nonseminomatous TGCT who was successfully treated with a partial orchiectomy followed by low-dose radiation with preservation of his testosterone production.

Original languageEnglish (US)
Article numbere27872
JournalPediatric Blood and Cancer
Volume66
Issue number10
DOIs
StatePublished - 2019

Keywords

  • germ cell tumors
  • pediatric oncology
  • radiation oncology
  • radiation therapy
  • solid tumors

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

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