Successful treatment of refractory disseminated Mycobacterium avium complex infection with the addition of linezolid and mefloquine

Esteban C. Nannini; Michael Keating; Peter Binstock; George Samonis; Dimitrios P. Kontoyiannis

doi:10.1053/jinf.2002.0970

Successful treatment of refractory disseminated Mycobacterium avium complex infection with the addition of linezolid and mefloquine

Esteban C. Nannini, Michael Keating, Peter Binstock, George Samonis, Dimitrios P. Kontoyiannis

Infectious Diseases, Infection Control, and Employee Health

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

Abstract

Except in patients with AIDS, disseminated MAC infection has been rare. We describe a patient with chronic lymphatic leukemia who developed disseminated cutaneous MAC lesions refractory to conventional antimycobacterial therapy. The lesions responded to the addition of compounds that were recently discovered to have anti-MAC activity (linezolid, mefloquine, moxifloxacin) as well as GM-CSF.

Original language	English (US)
Pages (from-to)	201-203
Number of pages	3
Journal	Journal of Infection
Volume	44
Issue number	3
DOIs	https://doi.org/10.1053/jinf.2002.0970
State	Published - Apr 2002

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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10.1053/jinf.2002.0970

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abstract = "Except in patients with AIDS, disseminated MAC infection has been rare. We describe a patient with chronic lymphatic leukemia who developed disseminated cutaneous MAC lesions refractory to conventional antimycobacterial therapy. The lesions responded to the addition of compounds that were recently discovered to have anti-MAC activity (linezolid, mefloquine, moxifloxacin) as well as GM-CSF.",

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AU - Samonis, George

AU - Kontoyiannis, Dimitrios P.

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AB - Except in patients with AIDS, disseminated MAC infection has been rare. We describe a patient with chronic lymphatic leukemia who developed disseminated cutaneous MAC lesions refractory to conventional antimycobacterial therapy. The lesions responded to the addition of compounds that were recently discovered to have anti-MAC activity (linezolid, mefloquine, moxifloxacin) as well as GM-CSF.

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Successful treatment of refractory disseminated Mycobacterium avium complex infection with the addition of linezolid and mefloquine

Abstract

ASJC Scopus subject areas

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