TY - JOUR
T1 - Sunitinib-induced acute hemolysis without hypertension
T2 - A case report
AU - Jain, Rajul
AU - Mathew, Paul
AU - Wood, Christopher G.
AU - Tannir, Nizar M.
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2008
Y1 - 2008
N2 - Sunitinib-associated hematologic adverse events are well known and include leukopenia, neutropenia, thrombocytopenia, anemia, and lymphopenia. Herein, we report the case of a patient with metastatic renal cell carcinoma who was treated with sunitinib and developed severe hemolysis without hypertension or reversible posterior leukoencephalopathy. Prompt discontinuation of the agent resulted in resolution of this complication.
AB - Sunitinib-associated hematologic adverse events are well known and include leukopenia, neutropenia, thrombocytopenia, anemia, and lymphopenia. Herein, we report the case of a patient with metastatic renal cell carcinoma who was treated with sunitinib and developed severe hemolysis without hypertension or reversible posterior leukoencephalopathy. Prompt discontinuation of the agent resulted in resolution of this complication.
KW - Anemia
KW - Renal cell carcinoma
KW - Targeted therapy
KW - Thrombotic microangiopathy
KW - Tyrosine kinase inhibitors
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UR - http://www.scopus.com/inward/citedby.url?scp=58149194185&partnerID=8YFLogxK
U2 - 10.3816/CGC.2008.n.019
DO - 10.3816/CGC.2008.n.019
M3 - Article
C2 - 18824436
AN - SCOPUS:58149194185
SN - 1558-7673
VL - 6
SP - 122
EP - 123
JO - Clinical Genitourinary Cancer
JF - Clinical Genitourinary Cancer
IS - 2
ER -