TY - JOUR
T1 - 99mTc-tilmanocept
T2 - A novel molecular agent for lymphatic mapping and sentinel lymph node localization
AU - Surasi, Devaki Shilpa
AU - O'Malley, Janis
AU - Bhambhvani, Pradeep
N1 - Publisher Copyright:
© 2015 by the Society of Nuclear Medicine and Molecular Imaging, Inc.
PY - 2015
Y1 - 2015
N2 - Preoperative lymphatic mapping in conjunction with intraoperative γ-probe detection is widely used for sentinel node localization in melanoma, breast cancer, and other malignancies. 99mTc-radiocolloids have been the standard radiotracers used for sentinel node mapping. 99mTc-tilmanocept is a receptorbinding molecular imaging agent approved by the U.S. Food and Drug Administration for lymphatic mapping and lymph node localization in breast cancer, melanoma, clinically nodenegative squamous cell carcinoma of the oral cavity, and other solid tumors. It has several advantages over conventional radiocolloids, including rapid injection site clearance, high sentinel node extraction, and low distal node accumulation, which can lead to efficient resource use.
AB - Preoperative lymphatic mapping in conjunction with intraoperative γ-probe detection is widely used for sentinel node localization in melanoma, breast cancer, and other malignancies. 99mTc-radiocolloids have been the standard radiotracers used for sentinel node mapping. 99mTc-tilmanocept is a receptorbinding molecular imaging agent approved by the U.S. Food and Drug Administration for lymphatic mapping and lymph node localization in breast cancer, melanoma, clinically nodenegative squamous cell carcinoma of the oral cavity, and other solid tumors. It has several advantages over conventional radiocolloids, including rapid injection site clearance, high sentinel node extraction, and low distal node accumulation, which can lead to efficient resource use.
KW - Lymphoseek
KW - Molecular imaging
KW - Sentinel lymph node mapping
KW - Tc-tilmanocept
UR - http://www.scopus.com/inward/record.url?scp=84930846367&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84930846367&partnerID=8YFLogxK
U2 - 10.2967/jnmt.115.155960
DO - 10.2967/jnmt.115.155960
M3 - Article
C2 - 25956693
AN - SCOPUS:84930846367
SN - 0091-4916
VL - 43
SP - 87
EP - 91
JO - Journal of nuclear medicine technology
JF - Journal of nuclear medicine technology
IS - 2
ER -