TY - GEN
T1 - Surface-based method to evaluate global brain shape asymmetries in human and chimpanzee brains
AU - Fournier, Marc
AU - Combès, Benoît
AU - Roberts, Neil
AU - Keller, Simon
AU - Crow, Tim J.
AU - Hopkins, William D.
AU - Prima, Sylvain
PY - 2011
Y1 - 2011
N2 - In this paper we use humans and chimpanzees brain MRI databases to develop methods for evaluating global brain asymmetries. We perform brain segmentation and hemispheric surface extraction on both populations. The human brain segmentation pipeline is adapted to chimpanzees in order to obtain results of good quality. To alleviate the problems due to cortical variability we propose a mesh processing algorithm to compute the brain global shape. Surface-based global brain asymmetries are computed on chimpanzee and human subjects using individual mid-sagittal plane evaluation and population-level mean shape estimation. Asymmetry results are presented in terms of axis-wise components in order to perform more specific evaluation and comparison between the two populations.
AB - In this paper we use humans and chimpanzees brain MRI databases to develop methods for evaluating global brain asymmetries. We perform brain segmentation and hemispheric surface extraction on both populations. The human brain segmentation pipeline is adapted to chimpanzees in order to obtain results of good quality. To alleviate the problems due to cortical variability we propose a mesh processing algorithm to compute the brain global shape. Surface-based global brain asymmetries are computed on chimpanzee and human subjects using individual mid-sagittal plane evaluation and population-level mean shape estimation. Asymmetry results are presented in terms of axis-wise components in order to perform more specific evaluation and comparison between the two populations.
KW - Axis-wise asymmetry components
KW - Brain global shape computation
KW - Chimp and human asymmetries comparison
KW - Chimps MRI brain segmentation
KW - Surfaced-based bilateral brain asymmetries
UR - http://www.scopus.com/inward/record.url?scp=80055060853&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80055060853&partnerID=8YFLogxK
U2 - 10.1109/ISBI.2011.5872412
DO - 10.1109/ISBI.2011.5872412
M3 - Conference contribution
AN - SCOPUS:80055060853
SN - 9781424441280
T3 - Proceedings - International Symposium on Biomedical Imaging
SP - 310
EP - 316
BT - 2011 8th IEEE International Symposium on Biomedical Imaging
T2 - 2011 8th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI'11
Y2 - 30 March 2011 through 2 April 2011
ER -