Synthesis of deuterium-labelled trantinterol

Hongliang Wen; Li Pan; Yingdan Zhang; Jiacheng Ma; Liqiong Qin; Maosheng Cheng

doi:10.1002/jlcr.1796

Synthesis of deuterium-labelled trantinterol

Hongliang Wen, Li Pan, Yingdan Zhang, Jiacheng Ma, Liqiong Qin, Maosheng Cheng

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Trantinterol, a selective β₂-adrenoceptor agonist, is currently in Phase II clinical trials for the treatment of asthma and bronchitis. The synthesis of deuterium-labelled trantinterol is described. The labelled trantinterol is used as an internal standard for the analysis and metabolic studies.

Original language	English (US)
Pages (from-to)	779-781
Number of pages	3
Journal	Journal of Labelled Compounds and Radiopharmaceuticals
Volume	53
Issue number	13
DOIs	https://doi.org/10.1002/jlcr.1796
State	Published - Nov 2010
Externally published	Yes

Keywords

deuterium
labelled
synthesis
trantinterol

ASJC Scopus subject areas

Analytical Chemistry
Biochemistry
Radiology Nuclear Medicine and imaging
Drug Discovery
Spectroscopy
Organic Chemistry

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10.1002/jlcr.1796

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abstract = "Trantinterol, a selective β2-adrenoceptor agonist, is currently in Phase II clinical trials for the treatment of asthma and bronchitis. The synthesis of deuterium-labelled trantinterol is described. The labelled trantinterol is used as an internal standard for the analysis and metabolic studies.",

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AU - Wen, Hongliang

AU - Pan, Li

AU - Zhang, Yingdan

AU - Ma, Jiacheng

AU - Qin, Liqiong

AU - Cheng, Maosheng

PY - 2010/11

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KW - deuterium

KW - labelled

KW - synthesis

KW - trantinterol

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Synthesis of deuterium-labelled trantinterol

Abstract

Keywords

ASJC Scopus subject areas

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