TY - JOUR
T1 - T-cell/histiocyte-rich large B-cell lymphoma in a child
T2 - A case report and review of literature
AU - Wei, Chapman
AU - Wei, Chaplin
AU - Alhalabi, Omar
AU - Chen, Lei
N1 - Publisher Copyright:
© The Author(s) 2018.
PY - 2018
Y1 - 2018
N2 - T-cell/histiocyte-rich large B-cell lymphoma is uncommon in children population. There were few cases reported in the literature with wide range clinical presentations including advanced stage, and more involvement of liver, spleen and bone marrow. Head and neck lymphadenopathy tends to present in younger children. We report a case of 10-year-old boy who initially presented intermittent fever, headaches and neck lymphadenopathy. Subsequently, he developed diffuse lymphadenopathy and hepatosplenomegaly. T-cell/histiocyte-rich large B-cell lymphoma was diagnosed on a cervical lymph node biopsy. Cervical lymphadenopathy in this age group is most commonly reactive or nonmalignant processes. Lymphoma is much less frequent; mainly are non-Hodgkin lymphomas. However, a subset of large B-cell lymphoma called T-cell/histiocyte- rich B-cell lymphoma is rare in children.
AB - T-cell/histiocyte-rich large B-cell lymphoma is uncommon in children population. There were few cases reported in the literature with wide range clinical presentations including advanced stage, and more involvement of liver, spleen and bone marrow. Head and neck lymphadenopathy tends to present in younger children. We report a case of 10-year-old boy who initially presented intermittent fever, headaches and neck lymphadenopathy. Subsequently, he developed diffuse lymphadenopathy and hepatosplenomegaly. T-cell/histiocyte-rich large B-cell lymphoma was diagnosed on a cervical lymph node biopsy. Cervical lymphadenopathy in this age group is most commonly reactive or nonmalignant processes. Lymphoma is much less frequent; mainly are non-Hodgkin lymphomas. However, a subset of large B-cell lymphoma called T-cell/histiocyte- rich B-cell lymphoma is rare in children.
KW - Head and neck lymphadenopathy
KW - Pediatric
KW - T-cell/histiocyte-rich large B-cell lymphoma
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U2 - 10.12998/wjcc.v6.i6.121
DO - 10.12998/wjcc.v6.i6.121
M3 - Article
C2 - 29988902
AN - SCOPUS:85054659829
SN - 2307-8960
VL - 6
SP - 121
EP - 126
JO - World Journal of Clinical Cases
JF - World Journal of Clinical Cases
IS - 6
ER -