Targeting the mTOR Pathway for the Prevention of ER-Negative Breast Cancer

Abhijit Mazumdar, William M. Tahaney, Jamal L. Hill, Yun Zhang, Sumankalai Ramachandran, Jitesh Kawedia, Jing Qian, Alejandro Contreras, Michelle I. Savage, Lana A. Vornik, Shizuko Sei, Altaf Mohammed, Powel H. Brown

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

PREVENTION RELEVANCE: Our results show that everolimus delays mammary tumor formation in multiple mouse models, suggesting that mTOR inhibitors will be useful for the prevention of ER-negative and triple-negative breast cancer in humans. See related Spotlight, p. 787.

Original languageEnglish (US)
Pages (from-to)791-802
Number of pages12
JournalCancer prevention research (Philadelphia, Pa.)
Volume15
Issue number12
DOIs
StatePublished - Dec 1 2022

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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