Technetium-99m-MIBI versus fluorine-18-FDG in diffuse multiple myeloma

Ayda M. El-Shirbiny; Henry Yeung; Massimo Imbriaco; Joseph Michaeli; Homer Macapinlac; Steven M. Larson

Technetium-99m-MIBI versus fluorine-18-FDG in diffuse multiple myeloma

Ayda M. El-Shirbiny, Henry Yeung, Massimo Imbriaco, Joseph Michaeli, Homer Macapinlac, Steven M. Larson

Research output: Contribution to journal › Article › peer-review

Abstract

Experience of scintigraphic detection of bone lesion and active bone marrow involvement of multiple myeloma, especially with sestamibi and FDG- PET scans is in evolution. We report a case of intense sestamibi uptake in bone marrow correlating with the extent of the disease, while FDG-PET scans showed activity only in areas of active disease progression associated with pain. Technetium-99m-sestamibi appears to indicate the extent of the disease, while [¹⁸F]FDG-PET scans show sites of active tumor proliferation and may be useful in directing local therapy such as radiation.

Original language	English (US)
Pages (from-to)	1208-1210
Number of pages	3
Journal	Journal of Nuclear Medicine
Volume	38
Issue number	8
State	Published - 1997
Externally published	Yes

Keywords

Fluorine-18-FDG
Multiple myeloma
PET
Sestamibi

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

Cite this

@article{f78bdcb1007d4e0c9c1c0a1b4f98cb6e,

title = "Technetium-99m-MIBI versus fluorine-18-FDG in diffuse multiple myeloma",

abstract = "Experience of scintigraphic detection of bone lesion and active bone marrow involvement of multiple myeloma, especially with sestamibi and FDG- PET scans is in evolution. We report a case of intense sestamibi uptake in bone marrow correlating with the extent of the disease, while FDG-PET scans showed activity only in areas of active disease progression associated with pain. Technetium-99m-sestamibi appears to indicate the extent of the disease, while [18F]FDG-PET scans show sites of active tumor proliferation and may be useful in directing local therapy such as radiation.",

keywords = "Fluorine-18-FDG, Multiple myeloma, PET, Sestamibi",

author = "El-Shirbiny, {Ayda M.} and Henry Yeung and Massimo Imbriaco and Joseph Michaeli and Homer Macapinlac and Larson, {Steven M.}",

year = "1997",

language = "English (US)",

volume = "38",

pages = "1208--1210",

journal = "Journal of Nuclear Medicine",

issn = "0161-5505",

publisher = "Society of Nuclear Medicine Inc.",

number = "8",

}

TY - JOUR

T1 - Technetium-99m-MIBI versus fluorine-18-FDG in diffuse multiple myeloma

AU - El-Shirbiny, Ayda M.

AU - Yeung, Henry

AU - Imbriaco, Massimo

AU - Michaeli, Joseph

AU - Macapinlac, Homer

AU - Larson, Steven M.

PY - 1997

Y1 - 1997

N2 - Experience of scintigraphic detection of bone lesion and active bone marrow involvement of multiple myeloma, especially with sestamibi and FDG- PET scans is in evolution. We report a case of intense sestamibi uptake in bone marrow correlating with the extent of the disease, while FDG-PET scans showed activity only in areas of active disease progression associated with pain. Technetium-99m-sestamibi appears to indicate the extent of the disease, while [18F]FDG-PET scans show sites of active tumor proliferation and may be useful in directing local therapy such as radiation.

AB - Experience of scintigraphic detection of bone lesion and active bone marrow involvement of multiple myeloma, especially with sestamibi and FDG- PET scans is in evolution. We report a case of intense sestamibi uptake in bone marrow correlating with the extent of the disease, while FDG-PET scans showed activity only in areas of active disease progression associated with pain. Technetium-99m-sestamibi appears to indicate the extent of the disease, while [18F]FDG-PET scans show sites of active tumor proliferation and may be useful in directing local therapy such as radiation.

KW - Fluorine-18-FDG

KW - Multiple myeloma

KW - PET

KW - Sestamibi

UR - http://www.scopus.com/inward/record.url?scp=0030824784&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030824784&partnerID=8YFLogxK

M3 - Article

C2 - 9255151

AN - SCOPUS:0030824784

SN - 0161-5505

VL - 38

SP - 1208

EP - 1210

JO - Journal of Nuclear Medicine

JF - Journal of Nuclear Medicine

IS - 8

ER -

Technetium-99m-MIBI versus fluorine-18-FDG in diffuse multiple myeloma

Abstract

Keywords

ASJC Scopus subject areas

Other files and links

Fingerprint

Cite this