Terpenes of the genus salvia: Cytotoxicity and antitumoral effects

Nimsi Campos-Xolalpa; Salud Pérez-Gutiérrez; Cuauhtémoc Pérez-González; Julia Mendoza-Pérez; Angel Josabad Alonso-Castro

doi:10.1007/978-981-10-8064-7_8

Terpenes of the genus salvia: Cytotoxicity and antitumoral effects

Nimsi Campos-Xolalpa, Salud Pérez-Gutiérrez, Cuauhtémoc Pérez-González, Julia Mendoza-Pérez, Angel Josabad Alonso-Castro

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2 Scopus citations

Abstract

Plants are an important source of natural compounds used in cancer chemotherapy. The Salvia genus includes around 900 species worldwide and is an important source of terpenes, a group of secondary metabolites. According to an estimate, 111 terpenes are isolated from 24 Salvia species till date, and only 48 terpenes showed the cytotoxic activity. Out of 24 species, 16 are the native of Asia and 7 of America and 1 is from Europe. On the basis of the chemical compounds, 82 correspond to diterpenes, 4 sesterpenoids, 16 sesquiterpenes, and 9 triterpenes. Out of total diterpenes, five (ferruginol, sclareol, cryptotanshinone, tanshinone I, and tanshinone IIA) have been tested for their antitumoral effect. The present chapter described detail account of terpenes isolated from plants of the Salvia genus with their cytotoxic and antitumor activity.

Original language	English (US)
Title of host publication	Anticancer Plants
Subtitle of host publication	Natural Products and Biotechnological Implements
Publisher	Springer Singapore
Pages	163-205
Number of pages	43
Volume	2
ISBN (Electronic)	9789811080647
ISBN (Print)	9789811080630
DOIs	https://doi.org/10.1007/978-981-10-8064-7_8
State	Published - Jan 1 2018
Externally published	Yes

Keywords

Antitumor activity
Cancer
Cytotoxic
Diterpenes
Sesquiterpenes

ASJC Scopus subject areas

General Agricultural and Biological Sciences
General Engineering
General Biochemistry, Genetics and Molecular Biology
General Medicine

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10.1007/978-981-10-8064-7_8

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abstract = "Plants are an important source of natural compounds used in cancer chemotherapy. The Salvia genus includes around 900 species worldwide and is an important source of terpenes, a group of secondary metabolites. According to an estimate, 111 terpenes are isolated from 24 Salvia species till date, and only 48 terpenes showed the cytotoxic activity. Out of 24 species, 16 are the native of Asia and 7 of America and 1 is from Europe. On the basis of the chemical compounds, 82 correspond to diterpenes, 4 sesterpenoids, 16 sesquiterpenes, and 9 triterpenes. Out of total diterpenes, five (ferruginol, sclareol, cryptotanshinone, tanshinone I, and tanshinone IIA) have been tested for their antitumoral effect. The present chapter described detail account of terpenes isolated from plants of the Salvia genus with their cytotoxic and antitumor activity.",

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AU - Pérez-González, Cuauhtémoc

AU - Mendoza-Pérez, Julia

AU - Alonso-Castro, Angel Josabad

N1 - Publisher Copyright: © Springer Nature Singapore Pte Ltd. 2018.

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N2 - Plants are an important source of natural compounds used in cancer chemotherapy. The Salvia genus includes around 900 species worldwide and is an important source of terpenes, a group of secondary metabolites. According to an estimate, 111 terpenes are isolated from 24 Salvia species till date, and only 48 terpenes showed the cytotoxic activity. Out of 24 species, 16 are the native of Asia and 7 of America and 1 is from Europe. On the basis of the chemical compounds, 82 correspond to diterpenes, 4 sesterpenoids, 16 sesquiterpenes, and 9 triterpenes. Out of total diterpenes, five (ferruginol, sclareol, cryptotanshinone, tanshinone I, and tanshinone IIA) have been tested for their antitumoral effect. The present chapter described detail account of terpenes isolated from plants of the Salvia genus with their cytotoxic and antitumor activity.

AB - Plants are an important source of natural compounds used in cancer chemotherapy. The Salvia genus includes around 900 species worldwide and is an important source of terpenes, a group of secondary metabolites. According to an estimate, 111 terpenes are isolated from 24 Salvia species till date, and only 48 terpenes showed the cytotoxic activity. Out of 24 species, 16 are the native of Asia and 7 of America and 1 is from Europe. On the basis of the chemical compounds, 82 correspond to diterpenes, 4 sesterpenoids, 16 sesquiterpenes, and 9 triterpenes. Out of total diterpenes, five (ferruginol, sclareol, cryptotanshinone, tanshinone I, and tanshinone IIA) have been tested for their antitumoral effect. The present chapter described detail account of terpenes isolated from plants of the Salvia genus with their cytotoxic and antitumor activity.

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KW - Sesquiterpenes

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Terpenes of the genus salvia: Cytotoxicity and antitumoral effects

Abstract

Keywords

ASJC Scopus subject areas

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