Testicular cancer

Robert J. Motzer; Neeraj Agarwal; Clair Beard; Graeme B. Bolger; Barry Boston; Michael A. Carducci; Toni K. Choueiri; Robert A. Figlin; Mayer Fishman; Steven L. Hancock; Gary R. Hudes; Eric Jonasch; Anne Kessinger; Timothy M. Kuzel; Paul H. Lange; Ellis G. Levine; Kim A. Margolin; M. Dror Michaelson; Thomas Olencki; Roberto Pili; Bruce G. Redman; Cary N. Robertson; Lawrence H. Schwartz; Joel Sheinfeld; Jue Wang

doi:10.6004/jnccn.2009.0047

Testicular cancer

Robert J. Motzer, Neeraj Agarwal, Clair Beard, Graeme B. Bolger, Barry Boston, Michael A. Carducci, Toni K. Choueiri, Robert A. Figlin, Mayer Fishman, Steven L. Hancock, Gary R. Hudes, Eric Jonasch, Anne Kessinger, Timothy M. Kuzel, Paul H. Lange, Ellis G. Levine, Kim A. Margolin, M. Dror Michaelson, Thomas Olencki, Roberto PiliBruce G. Redman, Cary N. Robertson, Lawrence H. Schwartz, Joel Sheinfeld, Jue Wang

Genitourinary Medical Oncology

Research output: Contribution to journal › Review article › peer-review

98 Scopus citations

Abstract

An estimated 8090 new cases of testicular cancer were diagnosed in the United States in 2008. Although relatively uncommon overall, germ cell tumors (GCTs) constitute the most common solid tumor in men between the ages of 15 and 34 years. The worldwide incidence of these tumors has more than doubled in the past 40 years. More than 90% of patients diagnosed with GCTs are cured, including 70% to 80% of patients with advanced tumors who are treated with chemotherapy. Standard therapy has been established at essentially all stages of management and must be closely followed to ensure the potential for cure. Updates to the 2009 NCCN Guidelines include the addition of doses for single-agent carboplatin for seminoma and changes to category 1 for recommendations on radiotherapy and surveillance.

Original language	English (US)
Pages (from-to)	672-693
Number of pages	22
Journal	JNCCN Journal of the National Comprehensive Cancer Network
Volume	7
Issue number	6
DOIs	https://doi.org/10.6004/jnccn.2009.0047
State	Published - Jun 2009

Keywords

Alpha-fetoprotein
Cisplatin
Germ cell tumors
Human chorionic gonadotropin
Lactate dehydrogenase
NCCN Clinical Practice Guidelines
Nonseminoma
Seminoma
Testicular cancer

ASJC Scopus subject areas

Oncology

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10.6004/jnccn.2009.0047

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Motzer, R. J., Agarwal, N., Beard, C., Bolger, G. B., Boston, B., Carducci, M. A., Choueiri, T. K., Figlin, R. A., Fishman, M., Hancock, S. L., Hudes, G. R., Jonasch, E., Kessinger, A., Kuzel, T. M., Lange, P. H., Levine, E. G., Margolin, K. A., Michaelson, M. D., Olencki, T., ... Wang, J. (2009). Testicular cancer. JNCCN Journal of the National Comprehensive Cancer Network, 7(6), 672-693. https://doi.org/10.6004/jnccn.2009.0047

Motzer, RJ, Agarwal, N, Beard, C, Bolger, GB, Boston, B, Carducci, MA, Choueiri, TK, Figlin, RA, Fishman, M, Hancock, SL, Hudes, GR, Jonasch, E, Kessinger, A, Kuzel, TM, Lange, PH, Levine, EG, Margolin, KA, Michaelson, MD, Olencki, T, Pili, R, Redman, BG, Robertson, CN, Schwartz, LH, Sheinfeld, J & Wang, J 2009, 'Testicular cancer', JNCCN Journal of the National Comprehensive Cancer Network, vol. 7, no. 6, pp. 672-693. https://doi.org/10.6004/jnccn.2009.0047

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abstract = "An estimated 8090 new cases of testicular cancer were diagnosed in the United States in 2008. Although relatively uncommon overall, germ cell tumors (GCTs) constitute the most common solid tumor in men between the ages of 15 and 34 years. The worldwide incidence of these tumors has more than doubled in the past 40 years. More than 90% of patients diagnosed with GCTs are cured, including 70% to 80% of patients with advanced tumors who are treated with chemotherapy. Standard therapy has been established at essentially all stages of management and must be closely followed to ensure the potential for cure. Updates to the 2009 NCCN Guidelines include the addition of doses for single-agent carboplatin for seminoma and changes to category 1 for recommendations on radiotherapy and surveillance.",

keywords = "Alpha-fetoprotein, Cisplatin, Germ cell tumors, Human chorionic gonadotropin, Lactate dehydrogenase, NCCN Clinical Practice Guidelines, Nonseminoma, Seminoma, Testicular cancer",

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AU - Michaelson, M. Dror

AU - Olencki, Thomas

AU - Pili, Roberto

AU - Redman, Bruce G.

AU - Robertson, Cary N.

AU - Schwartz, Lawrence H.

AU - Sheinfeld, Joel

AU - Wang, Jue

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Testicular cancer

Abstract

Keywords

ASJC Scopus subject areas

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