Abstract
Controversy surrounds the recent 2007 WHO Classification of Tumours of the Nervous System. A number of nosologic issues remain to be resolved, some a reflection of conceptual disagreement, others the result of inadequate data to permit their definitive resolution. Among these and discussed herein are (i) the nosologic place of highly anaplastic oligoastrocytic tumors, (ii) the forms and significance of microvascular changes in high-grade gliomas, (iii) the makeup of the glioneuronal tumors category, (iv) the subclassification of pineal parenchymal tumors of intermediate type, and (v) the classification of principle forms of mesenchymal neoplasms, specifically hemangiopericytoma and solitary fibrous tumor. These issues and others are the substance of this and an upcoming companion article.
Original language | English (US) |
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Pages (from-to) | 307-316 |
Number of pages | 10 |
Journal | Brain Pathology |
Volume | 18 |
Issue number | 3 |
DOIs | |
State | Published - Jul 2008 |
Keywords
- Brain tumors
- Classification
- Controversial issues
- Pathology
- World Health Organization
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- General Neuroscience
- Clinical Neurology