TY - JOUR
T1 - The Cancer Genome Atlas (TCGA)
T2 - An immeasurable source of knowledge
AU - Tomczak, Katarzyna
AU - Czerwińska, Patrycja
AU - Wiznerowicz, Maciej
PY - 2015
Y1 - 2015
N2 - The Cancer Genome Atlas (TCGA) is a public funded project that aims to catalogue and discover major cancer-causing genomic alterations to create a comprehensive "atlas" of cancer genomic profiles. So far, TCGA researchers have analysed large cohorts of over 30 human tumours through large-scale genome sequencing and integrated multi-dimensional analyses. Studies of individual cancer types, as well as comprehensive pan-cancer analyses have extended current knowledge of tumorigenesis. A major goal of the project was to provide publicly available datasets to help improve diagnostic methods, treatment standards, and finally to prevent cancer. This review discusses the current status of TCGA Research Network structure, purpose, and achievements.
AB - The Cancer Genome Atlas (TCGA) is a public funded project that aims to catalogue and discover major cancer-causing genomic alterations to create a comprehensive "atlas" of cancer genomic profiles. So far, TCGA researchers have analysed large cohorts of over 30 human tumours through large-scale genome sequencing and integrated multi-dimensional analyses. Studies of individual cancer types, as well as comprehensive pan-cancer analyses have extended current knowledge of tumorigenesis. A major goal of the project was to provide publicly available datasets to help improve diagnostic methods, treatment standards, and finally to prevent cancer. This review discusses the current status of TCGA Research Network structure, purpose, and achievements.
KW - Big data analysis
KW - Cancer genomics
KW - The Cancer Genome Atlas (TCGA)
UR - http://www.scopus.com/inward/record.url?scp=84981294341&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84981294341&partnerID=8YFLogxK
U2 - 10.5114/wo.2014.47136
DO - 10.5114/wo.2014.47136
M3 - Review article
C2 - 25691825
AN - SCOPUS:84981294341
SN - 1428-2526
VL - 1A
SP - A68-A77
JO - Wspolczesna Onkologia
JF - Wspolczesna Onkologia
ER -