Abstract
The possibility of the combined effects on the alveolar macrophage cytotoxicity due to zinc and Ni-coal dust was studied. The parameters in the experiments were cellular ATP level in alveolar macrophage (AM), cellular K+ and Zn++ in AM and the surface morphological changes of AM. The experimental results showed that low zinc can protect the toxicity of Ni-coal dust on AM, and that the protective effects on the toxicity of Ni-coal dust by zinc are dependent on its dosage. The ATP level and K+ content in AM are sensitive indices in reflecting the cytotoxicity and can be used in detecting environmental toxic substances.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 754-758 |
| Number of pages | 5 |
| Journal | Chinese medical journal |
| Volume | 103 |
| Issue number | 9 |
| State | Published - 1990 |
ASJC Scopus subject areas
- General Medicine