TY - JOUR
T1 - The extent of retinal involvement of canthaxanthin crystalline retinopathy demonstrated by multimodal imaging
AU - Iyer, Prashanth G.
AU - Shen, Mengxi
AU - Trivizki, Omer
AU - Barikian, Anita
AU - Chaudhry, Amina
AU - Rosenfeld, Philip J.
AU - Yehoshua, Zohar
N1 - Funding Information:
Originally submitted July 8, 2020. Revision received October 16, 2020. Accepted for publication October 22, 2020. Supported by grants from Carl Zeiss Meditec, the Salah Foundation, an unrestricted grant from the Research to Prevent Blindness, and the National Eye Institute Center Core Grant (P30EY014801) to the Department of Ophthalmology, University of Miami Miller School of Medicine. The funding organizations had no role in the design or conduct of the present research. Dr. Rosenfeld receives research support from Carl Zeiss Meditec, and the University of Miami co-owns a patent that is licensed to Carl Zeiss Meditec. Dr. Rosenfeld also receives grant support from Stealth Bio Therapeutics and is a consultant for Apellis, Biogen, Boehringer-Ingelheim, Carl Zeiss Meditec, Chengdu Kanghong Biotech, EyePoint, Ocunexus Therapeutics, Ocudyne, and Unity Biotechnology. He has equity interests in Apellis, Ocu-dyne, Valitor, and Verana Health. The remaining authors report no relevant financial disclosures. Address correspondence to Zohar Yehoshua, MD, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 Northwest 17th Street, Floor 1, Miami, FL 33136; email: ZYehoshua@med.miami.edu. doi: 10.3928/23258160-20201202-08
Publisher Copyright:
© 2020 Slack Incorporated. All rights reserved.
PY - 2020/12
Y1 - 2020/12
N2 - Limited information is known about the extent of canthaxanthin crystalline retinopathy on the retinal layers. The authors describe a 51-year-old woman who was taking canthaxanthin for tanning purposes for 7 years. Three years after cessation of this agent, she presented with asymmetric crystalline retinopathy affecting both eyes. She was lost to follow-up, and upon returning 4 years later, the crystalline retinopathy persisted but the number of crystals had decreased. Using swept-source optical coherence tomography, the authors showed that the crystalline retinopathy affected all retinal layers. In addition, retinal pigmented epithelial detachments were present suggesting persistent damage caused by the canthaxanthin.
AB - Limited information is known about the extent of canthaxanthin crystalline retinopathy on the retinal layers. The authors describe a 51-year-old woman who was taking canthaxanthin for tanning purposes for 7 years. Three years after cessation of this agent, she presented with asymmetric crystalline retinopathy affecting both eyes. She was lost to follow-up, and upon returning 4 years later, the crystalline retinopathy persisted but the number of crystals had decreased. Using swept-source optical coherence tomography, the authors showed that the crystalline retinopathy affected all retinal layers. In addition, retinal pigmented epithelial detachments were present suggesting persistent damage caused by the canthaxanthin.
UR - http://www.scopus.com/inward/record.url?scp=85098744173&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85098744173&partnerID=8YFLogxK
U2 - 10.3928/23258160-20201202-08
DO - 10.3928/23258160-20201202-08
M3 - Article
C2 - 33339055
AN - SCOPUS:85098744173
SN - 2325-8160
VL - 51
SP - 727
EP - 731
JO - Ophthalmic Surgery Lasers and Imaging Retina
JF - Ophthalmic Surgery Lasers and Imaging Retina
IS - 12
ER -