The family that eats together stays together: New p53 family transcriptional targets in autophagy

Marco Napoli; Elsa R. Flores

doi:10.1101/gad.219147.113

The family that eats together stays together: New p53 family transcriptional targets in autophagy

Marco Napoli, Elsa R. Flores

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

Autophagy is a biological process that is crucial to maintain cellular homeostasis and is regulated by several metabolic pathways, including the p53 tumor suppressor pathway. In this issue of Genes & Development, Kenzelmann Broz and colleagues (pp. 1016-1031) show how the p53 family as a whole, including p63 and p73, collaborate in controlling autophagy to support tumor suppression.

Original language	English (US)
Pages (from-to)	971-974
Number of pages	4
Journal	Genes and Development
Volume	27
Issue number	9
DOIs	https://doi.org/10.1101/gad.219147.113
State	Published - May 1 2013

Keywords

Autophagy
ChIP-seq
RNA-seq
Tumor suppression
p53

ASJC Scopus subject areas

Genetics
Developmental Biology

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10.1101/gad.219147.113

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AB - Autophagy is a biological process that is crucial to maintain cellular homeostasis and is regulated by several metabolic pathways, including the p53 tumor suppressor pathway. In this issue of Genes & Development, Kenzelmann Broz and colleagues (pp. 1016-1031) show how the p53 family as a whole, including p63 and p73, collaborate in controlling autophagy to support tumor suppression.

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KW - ChIP-seq

KW - RNA-seq

KW - Tumor suppression

KW - p53

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The family that eats together stays together: New p53 family transcriptional targets in autophagy

Abstract

Keywords

ASJC Scopus subject areas

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