TY - JOUR
T1 - The gene for the S7 ribosomal protein of Chlamydia trachomatis
T2 - characterization within the chlamydial sfr operon
AU - Wagar, E. A.
AU - Pang, M.
N1 - Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.
PY - 1992/2
Y1 - 1992/2
N2 - The prokaryotic ribosomal operon, str, contains open reading frames for the two elongation factors, elongation factor G (EF‐G) and elongation factor Tu (EF‐Tu), and ribosomal proteins 57 and S12. The DNA sequence and predicted amino acid sequence for S7 from Chlamydia trachomatis are presented and compared with homologues from other prokaryotes. Also, the relationship of the S7 gene to the open reading frames for ribosomal protein S12 and EF‐G is described. Significant amino acid homology is also noted when the amino‐terminal sequence of chlamydial EF‐G is compared with the cytoplasmic tetra‐cycline resistance factors, tetM and tetO, from streptococci and Campylobacter jejuni. Related findings and possible resistance mechanisms for the newly recognized tetracycline‐resistant clinical isolates of C. trachomatis are discussed.
AB - The prokaryotic ribosomal operon, str, contains open reading frames for the two elongation factors, elongation factor G (EF‐G) and elongation factor Tu (EF‐Tu), and ribosomal proteins 57 and S12. The DNA sequence and predicted amino acid sequence for S7 from Chlamydia trachomatis are presented and compared with homologues from other prokaryotes. Also, the relationship of the S7 gene to the open reading frames for ribosomal protein S12 and EF‐G is described. Significant amino acid homology is also noted when the amino‐terminal sequence of chlamydial EF‐G is compared with the cytoplasmic tetra‐cycline resistance factors, tetM and tetO, from streptococci and Campylobacter jejuni. Related findings and possible resistance mechanisms for the newly recognized tetracycline‐resistant clinical isolates of C. trachomatis are discussed.
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U2 - 10.1111/j.1365-2958.1992.tb01475.x
DO - 10.1111/j.1365-2958.1992.tb01475.x
M3 - Article
C2 - 1552847
AN - SCOPUS:0026542645
SN - 0950-382X
VL - 6
SP - 327
EP - 335
JO - Molecular Microbiology
JF - Molecular Microbiology
IS - 3
ER -