TY - JOUR
T1 - The human c-ros gene (ROS) is located at chromosome region 6q16→6q22
AU - Nagarajan, L.
AU - Louie, E.
AU - Tsujimoto, Y.
AU - Balduzzi, P. C.
AU - Huebner, K.
AU - Croce, C. M.
PY - 1986
Y1 - 1986
N2 - The human homolog, c-ros, of the transforming gene, v-ros, of the avian sarcoma virus, UR2, has been isolated from a human genomic library. A single-copy fragment from the human c-ros genomic clone has been used to map the human c-ros homolog (ROS) to human chromosome region 6q16→6q22 by somatic cell hybrid analysis and chromosomal in situ hybridization. Thus, the c-ros gene joins the c-myb oncogene, which is distal to the c-ros gene on the long arm of human chromosome 6, as a candidate for involvement in chromosome 6q deletions and rearrangements seen in various malignancies.
AB - The human homolog, c-ros, of the transforming gene, v-ros, of the avian sarcoma virus, UR2, has been isolated from a human genomic library. A single-copy fragment from the human c-ros genomic clone has been used to map the human c-ros homolog (ROS) to human chromosome region 6q16→6q22 by somatic cell hybrid analysis and chromosomal in situ hybridization. Thus, the c-ros gene joins the c-myb oncogene, which is distal to the c-ros gene on the long arm of human chromosome 6, as a candidate for involvement in chromosome 6q deletions and rearrangements seen in various malignancies.
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U2 - 10.1073/pnas.83.17.6568
DO - 10.1073/pnas.83.17.6568
M3 - Article
C2 - 3529088
AN - SCOPUS:0022970908
SN - 0027-8424
VL - 83
SP - 6568
EP - 6572
JO - Proceedings of the National Academy of Sciences of the United States of America
JF - Proceedings of the National Academy of Sciences of the United States of America
IS - 17
ER -