The immunogenicity of the 7E3 murine monoclonal Fab antibody fragment variable region is dramatically reduced in humans by substitution of human for murine constant regions

David M. Knight, Carrie Wagner, Robert Jordan, Mary Frances McAleer, Renato DeRita, David N. Fass, Barry S. Coller, Harlan F. Weisman, John Ghrayeb

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Medicine & Life Sciences