TY - JOUR
T1 - The International Association for the Study of Lung Cancer Pleural Mesothelioma Staging Project
T2 - Expanded Database to Inform Revisions in the Ninth Edition of the TNM Classification of Pleural Mesothelioma
AU - Members of the International Association for the Study of Lung Cancer Staging and Prognostic Factors Committee and Advisory Board and Participating Institutions
AU - Wolf, Andrea S.
AU - Eisele, Megan
AU - Giroux, Dorothy J.
AU - Gill, Ritu
AU - Nowak, Anna K.
AU - Bille, Andrea
AU - Rice, David
AU - Ripley, Robert T.
AU - Opitz, Isabelle
AU - Galateau-Salle, Francoise
AU - Hasegawa, Seiki
AU - Kindler, Hedy L.
AU - Pass, Harvey I.
AU - Rusch, Valerie W.
N1 - Publisher Copyright:
© 2024 International Association for the Study of Lung Cancer
PY - 2024
Y1 - 2024
N2 - The International Association for the Study of Lung Cancer collaborated with the International Mesothelioma Interest Group to propose the first TNM stage classification system for diffuse pleural mesothelioma in 1995, accepted by the Union for International Cancer Control and the American Joint Committee on Cancer for the sixth and seventh edition stage classification manuals. The International Association for the Study of Lung Cancer Staging and Prognostic Factors Committee Mesothelioma Domain developed and analyzed an international registry of patients with pleural mesothelioma and updated TNM descriptors for the eighth edition of the stage classification system. To inform revisions for the forthcoming ninth edition of the TNM stage classification system, data submission was solicited for patients diagnosed between 2013 and 2022 with expanded data elements on the basis of the first project's exploratory analyses, including pleural thickness measurements, updated surgical nomenclature, and molecular markers. The resulting database consisted of a total of 3598 analyzable cases from Europe, Australia, Asia, North America, and South America, with a median age of 71 years (range: 18–99 y), 2775 (77.1%) of whom were men. With only 1310 patients (36.4%) undergoing curative-intent operations, this iteration of the database includes far more patients treated nonsurgically compared with prior. Four separate manuscripts on T, N, M, and stage groupings submitted to this journal will summarize analyses of these data and will serve collectively as the primary source of the proposed changes to the upcoming ninth edition of the pleural mesothelioma stage classification system.
AB - The International Association for the Study of Lung Cancer collaborated with the International Mesothelioma Interest Group to propose the first TNM stage classification system for diffuse pleural mesothelioma in 1995, accepted by the Union for International Cancer Control and the American Joint Committee on Cancer for the sixth and seventh edition stage classification manuals. The International Association for the Study of Lung Cancer Staging and Prognostic Factors Committee Mesothelioma Domain developed and analyzed an international registry of patients with pleural mesothelioma and updated TNM descriptors for the eighth edition of the stage classification system. To inform revisions for the forthcoming ninth edition of the TNM stage classification system, data submission was solicited for patients diagnosed between 2013 and 2022 with expanded data elements on the basis of the first project's exploratory analyses, including pleural thickness measurements, updated surgical nomenclature, and molecular markers. The resulting database consisted of a total of 3598 analyzable cases from Europe, Australia, Asia, North America, and South America, with a median age of 71 years (range: 18–99 y), 2775 (77.1%) of whom were men. With only 1310 patients (36.4%) undergoing curative-intent operations, this iteration of the database includes far more patients treated nonsurgically compared with prior. Four separate manuscripts on T, N, M, and stage groupings submitted to this journal will summarize analyses of these data and will serve collectively as the primary source of the proposed changes to the upcoming ninth edition of the pleural mesothelioma stage classification system.
KW - Extrapleural pneumonectomy
KW - Mesothelioma
KW - Mesothelioma databases
KW - Pleurectomy/decortication
KW - Staging
KW - TNM classification
UR - http://www.scopus.com/inward/record.url?scp=85187341958&partnerID=8YFLogxK
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U2 - 10.1016/j.jtho.2024.01.018
DO - 10.1016/j.jtho.2024.01.018
M3 - Article
C2 - 38309456
AN - SCOPUS:85187341958
SN - 1556-0864
JO - Journal of Thoracic Oncology
JF - Journal of Thoracic Oncology
ER -