TY - JOUR
T1 - The noninvestigational use of tyrosine kinase inhibitors in thyroid cancer
T2 - Establishing a standard for patient safety and monitoring
AU - Carhill, Aubrey A.
AU - Cabanillas, Maria E.
AU - Jimenez, Camilo
AU - Waguespack, Steven G.
AU - Habra, Mouhammed A.
AU - Hu, Mimi
AU - Ying, Anita
AU - Vassilopoulou-Sellin, Rena
AU - Gagel, Robert F.
AU - Sherman, Steven I.
AU - Busaidy, Naifa L.
PY - 2013/1
Y1 - 2013/1
N2 - Context: The increasing use of tyrosine kinase inhibitor therapy outside of the context of the clinical trial for treatment of advanced thyroid cancer has highlighted the need for a systematic approach to the clinical application of these agents in order to improve patient safety and monitoring promote consistency among providers, and ensure compliance with both institutional and industry standards. Evidence: We reviewed professional thyroid cancer guidelines, the National Comprehensive Cancer Network task force reports, American Society of Clinical Oncology safety standards, review articles, and clinical trials published within the past 10 yr and also included relevant older studies. Conclusions: Review of available published data and the collective experience prescribing tyrosine kinase inhibitors at The University of Texas MD Anderson Cancer Center have highlighted the need for a systematic, comprehensive, and uniform approach to managing these patients. This paper discusses the approach adopted by the Department of Endocrine Neoplasia at the MD Anderson Cancer Center and illustrates practice patterns, experience, and our standardized approach related to prescribing commercially available tyrosine kinase inhibitors outside of the context of a clinical trial for patients with advanced thyroid cancer.
AB - Context: The increasing use of tyrosine kinase inhibitor therapy outside of the context of the clinical trial for treatment of advanced thyroid cancer has highlighted the need for a systematic approach to the clinical application of these agents in order to improve patient safety and monitoring promote consistency among providers, and ensure compliance with both institutional and industry standards. Evidence: We reviewed professional thyroid cancer guidelines, the National Comprehensive Cancer Network task force reports, American Society of Clinical Oncology safety standards, review articles, and clinical trials published within the past 10 yr and also included relevant older studies. Conclusions: Review of available published data and the collective experience prescribing tyrosine kinase inhibitors at The University of Texas MD Anderson Cancer Center have highlighted the need for a systematic, comprehensive, and uniform approach to managing these patients. This paper discusses the approach adopted by the Department of Endocrine Neoplasia at the MD Anderson Cancer Center and illustrates practice patterns, experience, and our standardized approach related to prescribing commercially available tyrosine kinase inhibitors outside of the context of a clinical trial for patients with advanced thyroid cancer.
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U2 - 10.1210/jc.2012-2909
DO - 10.1210/jc.2012-2909
M3 - Review article
C2 - 23185034
AN - SCOPUS:84872078679
SN - 0021-972X
VL - 98
SP - 31
EP - 42
JO - Journal of Clinical Endocrinology and Metabolism
JF - Journal of Clinical Endocrinology and Metabolism
IS - 1
ER -