The novel BMI-1 inhibitor PTC596 downregulates MCL-1 and induces p53-independent mitochondrial apoptosis in acute myeloid leukemia progenitor cells

Y. Nishida, A. Maeda, M. J. Kim, L. Cao, Y. Kubota, J. Ishizawa, A. AlRawi, Y. Kato, A. Iwama, M. Fujisawa, K. Matsue, M. Weetall, M. Dumble, M. Andreeff, T. W. Davis, A. Branstrom, S. Kimura, Kensuke Kojima

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