The Palliative Care of Patients with Brain Metastases

Metastases to the central nervous system (CNS) are a common and disabling complication of cancer. Most often occurring in the setting of advanced cancer, metastases to the brain or spinal cord impart a unique constellation of symptoms and challenges for patients and their caregivers. Cognitive dysfunction, sensorimotor impairment, seizures, and fatigue may all contribute to the disability this population experiences. Palliative care tending to the medical and psychosocial well-being of cancer patients should play a central role in their care. Both pharmacologic and non-pharmacologic interventions can reduce the symptom burden and improve the quality of life in this population. An awareness and understanding of the palliative care needs and interventions by clinicians are central to improving our care of patients with CNS metastases.