Abstract
Renal allograft rejection represents the combined efforts of cellular and humoral immunity. The tissue targets are the renal allograft vasculature, and to a lesser extent, the glomeruli. The temporal sequence and predominant pathophysiological features of rejection are clearly related to histocompatibility differences between the donor organ and recipient. A better understanding of these pathophysiological processes has given some insight into its immunological sequelae of rejection. However, despite the rapidly expanding knowledge about renal allograft rejection, many basic tenets and a specific therapeutic approach remain to be eludicated.
Original language | English (US) |
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Pages (from-to) | 350-380 |
Number of pages | 31 |
Journal | Journal of Surgical Research |
Volume | 12 |
Issue number | 5 |
DOIs | |
State | Published - May 1972 |
Externally published | Yes |
ASJC Scopus subject areas
- Surgery