TY - JOUR
T1 - The prevalence of altered body image in patients with primary brain tumors
T2 - an understudied population
AU - Rowe, Lindsay
AU - Vera, Elizabeth
AU - Acquaye, Alvina
AU - Crandon, Sonja
AU - Shah, Veeraj
AU - Bryla, Christine
AU - Wu, Jing
AU - Wall, Kathleen
AU - Siegel, Christine
AU - Reyes, Jennifer
AU - Penas-Prado, Marta
AU - Leggiero, Nicole
AU - Cordova, Christine
AU - Burton, Eric
AU - Antony, Ramya
AU - Boris, Lisa
AU - Aboud, Orwa
AU - Vyas, Yamini
AU - Mathen, Peter
AU - Gilbert, Mark
AU - Camphausen, Kevin
AU - Mendoza, Tito
AU - Armstrong, Terri
N1 - Publisher Copyright:
© 2020, The Author(s).
PY - 2020/4/1
Y1 - 2020/4/1
N2 - Purpose: Body image (BI) is an important issue for cancer patients, as patients with BI concerns are susceptible to depression, anxiety, difficulty coping, and poor quality of life (QoL). While this concern has been documented in patients with other malignancies, no data exists of this QoL issue in patients with primary brain tumors (PBT). Methods: A cross-sectional survey of 100 PBT patients was conducted on an IRB approved prospective protocol using structured questionnaires. Participants completed the body image scale (BIS), Appearance Scheme Inventory Revised (ASI-R), MD Anderson Symptom Inventory Brain Tumor (MDASI-BT), and Patient-Reported Outcomes Measurement Information System (PROMIS) Depression, Anxiety, and Psychosocial Impact Positive measures. Results: The prevalence of clinically significant body image dissatisfaction (BIS ≥ 10) was 28% (95% CI 19–37%), median BIS score was 5 (range 0–27). The median ASI-R composite score was 2.9 (range 1.5–4.7). BIS was significantly correlated with the ASI-R (r = 0.53, 95% CI 0.37 to 0.65). The mean PROMIS Depression score was 48.4 (SD = 8.9), PROMIS Anxiety score was 49.4 (SD = 9.9), and PROMIS Psychosocial Illness Impact Positive score was 48.9 (SD = 9.7). BIS was significantly correlated with age, and trended with BMI and sex. The PROMIS Psychosocial Illness Impact Positive and PROMIS Anxiety scores were the most strongly related to BIS. Conclusions: This study, the first to explore altered body image in PBT patients, revealed clinically significant body image dissatisfaction in nearly 1/3 of patients, similar to other malignancies. These findings underscore the potential contribution of disease and treatment-related body image concerns on psychosocial wellbeing in patients with PBT.
AB - Purpose: Body image (BI) is an important issue for cancer patients, as patients with BI concerns are susceptible to depression, anxiety, difficulty coping, and poor quality of life (QoL). While this concern has been documented in patients with other malignancies, no data exists of this QoL issue in patients with primary brain tumors (PBT). Methods: A cross-sectional survey of 100 PBT patients was conducted on an IRB approved prospective protocol using structured questionnaires. Participants completed the body image scale (BIS), Appearance Scheme Inventory Revised (ASI-R), MD Anderson Symptom Inventory Brain Tumor (MDASI-BT), and Patient-Reported Outcomes Measurement Information System (PROMIS) Depression, Anxiety, and Psychosocial Impact Positive measures. Results: The prevalence of clinically significant body image dissatisfaction (BIS ≥ 10) was 28% (95% CI 19–37%), median BIS score was 5 (range 0–27). The median ASI-R composite score was 2.9 (range 1.5–4.7). BIS was significantly correlated with the ASI-R (r = 0.53, 95% CI 0.37 to 0.65). The mean PROMIS Depression score was 48.4 (SD = 8.9), PROMIS Anxiety score was 49.4 (SD = 9.9), and PROMIS Psychosocial Illness Impact Positive score was 48.9 (SD = 9.7). BIS was significantly correlated with age, and trended with BMI and sex. The PROMIS Psychosocial Illness Impact Positive and PROMIS Anxiety scores were the most strongly related to BIS. Conclusions: This study, the first to explore altered body image in PBT patients, revealed clinically significant body image dissatisfaction in nearly 1/3 of patients, similar to other malignancies. These findings underscore the potential contribution of disease and treatment-related body image concerns on psychosocial wellbeing in patients with PBT.
KW - Body image
KW - Brain tumors
KW - Psychological distress
KW - Quality of life
UR - http://www.scopus.com/inward/record.url?scp=85083042249&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85083042249&partnerID=8YFLogxK
U2 - 10.1007/s11060-020-03433-8
DO - 10.1007/s11060-020-03433-8
M3 - Article
C2 - 32096067
AN - SCOPUS:85083042249
SN - 0167-594X
VL - 147
SP - 397
EP - 404
JO - Journal of neuro-oncology
JF - Journal of neuro-oncology
IS - 2
ER -