The prevention and treatment of radiotherapy-induced xerostomia

Avraham Eisbruch; Nelson Rhodus; David Rosenthal; Barbara Murphy; Coen Rasch; Stephen Sonis; Charles Scarantino; David Brizel

doi:10.1016/S1053-4296(03)00027-4

The prevention and treatment of radiotherapy-induced xerostomia

Avraham Eisbruch, Nelson Rhodus, David Rosenthal, Barbara Murphy, Coen Rasch, Stephen Sonis, Charles Scarantino, David Brizel

Radiation Oncology

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

Efforts to reduce the severity of postradiotherapy xerostomia include the use of salivary substitutes to gain symptomatic relief, salivary gland stimulants, agents delivered to protect the glands during radiotherapy (RT), and physical means to partially spare the major salivary glands from RT while adequately irradiating tumor targets. These means include advanced RT treatment planning and salivary tissue transfer to nonirradiated areas. The relative potential gain from each of these strategies is discussed in this article. The combination of partial salivary gland sparing and radiation protectors/stimulants may provide additive or synergistic gains in reducing the severity of xerostomia.

Original language	English (US)
Pages (from-to)	302-308
Number of pages	7
Journal	Seminars in radiation oncology
Volume	13
Issue number	3
DOIs	https://doi.org/10.1016/S1053-4296(03)00027-4
State	Published - Jul 2003

ASJC Scopus subject areas

Oncology
Radiology Nuclear Medicine and imaging
Cancer Research

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AU - Sonis, Stephen

AU - Scarantino, Charles

AU - Brizel, David

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The prevention and treatment of radiotherapy-induced xerostomia

Abstract

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