The removal of human leukaemia cells from blood using interdigitated microelectrodes

F. F. Becker; X. B. Wang; Y. Huang; R. Pethig; J. Vykoukal; P. R.C. Gascoyne

doi:10.1088/0022-3727/27/12/030

The removal of human leukaemia cells from blood using interdigitated microelectrodes

F. F. Becker, X. B. Wang, Y. Huang, R. Pethig, J. Vykoukal, P. R.C. Gascoyne

Translational Molecular Pathology

Research output: Contribution to journal › Article › peer-review

185 Scopus citations

Abstract

An electroaffinity column containing an interdigitated microelectrode array was used to retain human leukaemia cells dielectrophoretically and thereby separate them from normal blood cells. The leukaemic cells could be subsequently released by removal of the dielectrophoretic field and collected. This novel approach exploits the differential dielectric properties of cells as a sorting criterion and has applications in medicine, biotechnology and environmental settings.

Original language	English (US)
Pages (from-to)	2659-2662
Number of pages	4
Journal	Journal of Physics D: Applied Physics
Volume	27
Issue number	12
DOIs	https://doi.org/10.1088/0022-3727/27/12/030
State	Published - Dec 14 1994

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Acoustics and Ultrasonics
Surfaces, Coatings and Films

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The removal of human leukaemia cells from blood using interdigitated microelectrodes

Abstract

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